291 citations,
April 2010 in “Gastroenterology” Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.
220 citations,
March 2020 in “Advanced functional materials” Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.
137 citations,
April 2015 in “Nature Reviews Molecular Cell Biology” Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.
78 citations,
October 2012 in “Biomaterials” Larger spheroids improve hair growth, but size doesn't guarantee thicker hair.
54 citations,
August 2009 in “Dermatologic Surgery” Modern hair transplants use small grafts for a natural look and drugs to prevent further loss, with high patient satisfaction.
46 citations,
September 2010 in “Southern Medical Journal” Hair loss treatments include medications and new methods like low-level light therapy, which may work by boosting cell activity and blood flow.
43 citations,
October 2003 in “Journal of The American Academy of Dermatology” Hair transplanting is a useful, often overlooked treatment for female pattern hair loss.
31 citations,
July 2015 in “Clinical, Cosmetic and Investigational Dermatology” Hair restoration surgery effectively treats hair loss with natural-looking results, using techniques like stem cells and platelet-rich plasma.
25 citations,
April 2018 in “Journal of Cosmetic Dermatology” PRP injections increase hair density and diameter in female androgenetic alopecia patients.
25 citations,
May 2013 in “Journal of mammary gland biology and neoplasia” Hedgehog signaling is crucial for mammary gland development over hair follicles.
23 citations,
January 2020 in “Central-European Journal of Immunology/Central European Journal of Immunology” Alopecia areata, a type of hair loss, is likely an autoimmune disease with a genetic link, but its exact cause is still unknown.
17 citations,
December 2004 in “The Journal of Men's Health & Gender” Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.
17 citations,
January 1996 in “Aesthetic Plastic Surgery” The tumescent technique improves hair micrografting by providing lasting anesthesia, reducing bleeding, and increasing patient comfort.
15 citations,
December 2007 in “Dermatologic Therapy” Hair transplantation has improved with techniques that increase graft survival and patient satisfaction for more natural results.
15 citations,
February 2011 in “Journal of Tissue Engineering and Regenerative Medicine” The best method for transplanting skin cells to regenerate hair follicles is the Hemi-vascularized sandwich method, as it produces more mature follicles and promotes hair growth.
14 citations,
May 2014 in “Archives of plastic surgery” The position of the parietal whorl can predict safe donor areas for hair transplants in Korean men with male pattern baldness.
14 citations,
July 2009 in “Current Opinion in Otolaryngology & Head and Neck Surgery” Hair restoration techniques like follicular unit transplant surgery and follicular unit extraction are effective, with ideal graft placement density between 20-30 units per cm². Medications like Minoxidil and Finasteride can help maintain and regrow hair.
12 citations,
October 2017 in “Journal of Cosmetic Dermatology” Combining plasma rich in growth factors with hair transplant surgery may lead to faster recovery and better outcomes for hair loss treatment.
11 citations,
July 2008 in “Facial Plastic Surgery Clinics of North America” Hair restoration surgery redistributes existing hair to achieve a natural look, with visible regrowth in 3-4 months and rare complications, mostly aesthetic.
11 citations,
March 2014 in “Journal of Investigative Dermatology” Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.
8 citations,
January 2015 in “Scars, burns & healing” Hair transplantation effectively treats burn scar alopecia, improving self-esteem and confidence.
7 citations,
April 2015 in “Plastic and Aesthetic Nursing” Hair transplantation can effectively restore a natural-looking hairline when properly planned and executed.
7 citations,
June 1992 in “The Journal of Dermatologic Surgery and Oncology” Hair transplantation is a viable treatment for some types of female hair loss, with careful donor assessment and attention to psychological factors.
4 citations,
October 2018 in “Cell Stem Cell” Hox genes control hair growth patterns in mammals by regulating stem cell activity in the skin.
1 citations,
October 2018 in “European Journal of Plastic Surgery” The study found that hair transplant complications are rare, with swelling being the most common issue.
1 citations,
June 2017 in “Actas Dermo-Sifiliográficas” Follicular Unit Extraction (FUE) is a hair transplant method with less scarring and discomfort but requires skilled surgeons and has limitations on graft numbers per session.
1 citations,
January 2024 in “Theranostics” Exosomes show promise for future tissue regeneration.
1 citations,
January 2020 in “Skin appendage disorders” Hair transplants for male baldness can show inflammation and fibrosis, but more research is needed to confirm LPP presence.
1 citations,
November 2018 in “Elsevier eBooks” The document concludes that transplantology has evolved with improved techniques and materials, making transplants more successful and expanding the types of transplants possible.
The conclusion is that closing scalp wounds is possible, but restoring hair without donor material is still a major challenge.