110 citations,
October 2019 in “Translational Andrology and Urology” More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.
106 citations,
January 2016 in “Journal of Cosmetic Dermatology” Using platelet-rich plasma with microneedling works better for acne scars than microneedling with water.
102 citations,
July 2007 in “Genes & Development” A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.
90 citations,
October 1996 in “Dermatologic Clinics” Growth factors are crucial for hair development and could help treat hair diseases.
89 citations,
November 2017 in “Journal of Cellular Physiology” The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
88 citations,
June 2016 in “Human Reproduction Update” New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.
86 citations,
January 2019 in “Frontiers in Immunology” The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.
86 citations,
May 2013 in “American journal of obstetrics and gynecology” Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.
85 citations,
July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
74 citations,
June 2018 in “Cell death and disease” Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.
74 citations,
May 2004 in “Journal of Clinical Hypertension” Minoxidil effectively treats severe hypertension, but watch for side effects.
72 citations,
June 2001 in “Journal of Investigative Dermatology” S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.
71 citations,
September 2007 in “Cancer” Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.
67 citations,
January 2020 in “Cellular & Molecular Immunology/Cellular & molecular immunology” Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.
66 citations,
March 2009 in “British journal of surgery” Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.
66 citations,
January 2000 in “Hormone Research in Paediatrics” Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.
66 citations,
October 1984 in “Annual Review of Microbiology” Toxic Shock Syndrome cases increased due to new factors, but decreased with public health measures and changes in tampon use.
60 citations,
July 2011 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
57 citations,
March 2018 in “International Journal of Molecular Sciences” The extracellular matrix is crucial for controlling skin stem cell behavior and health.
57 citations,
January 1986 in “The Prostate” The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
54 citations,
October 2019 in “Cochrane library” Some drugs may reduce prostatitis symptoms short-term with few side effects.
54 citations,
July 2002 in “Clinical and Experimental Dermatology” DHT, a testosterone byproduct, causes male pattern baldness.
54 citations,
November 2001 in “Urology” The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.
53 citations,
February 2022 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” AMH helps estimate ovarian reserve but doesn't predict pregnancy chances; age is more important.
53 citations,
May 1987 in “The Lancet” The document suggests a possible link between Crohn's disease and Johne's disease and calls for more research.
52 citations,
January 2004 in “Medical mycology” The rise in tinea capitis cases in Stockholm is linked to increased African immigration.
52 citations,
September 1996 in “Obstetrics & Gynecology” People often struggle to consistently use contraceptives and other medications, and long-acting options might be better for those who want to avoid daily doses.
51 citations,
November 2011 in “British Journal of Dermatology” A gene called HDAC9 might be a new factor in male-pattern baldness.
50 citations,
March 2001 in “Clinics in Dermatology” Genes and hormones cause hair loss, with four genes contributing equally.
49 citations,
July 2004 in “Anesthesiology” The document concludes that more research is needed to understand how to treat muscle pain with drugs.