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β1 integrin may indicate and influence the severity of hair loss in androgenetic alopecia.

Significant progress was made in understanding PXE, but effective treatments are still needed.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Hair follicle stem cells have significant potential for treating various disorders.

The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.

KGF and activin are crucial for skin healing and repair.

Tight junctions create a barrier in pig hair follicles that controls what can enter the skin.

People with alopecia have shorter hair follicles and more c-kit, a stem cell factor receptor, which could predict how the condition progresses.

A new mutation in the STING protein causes a disease with lupus-like symptoms and responds well to a specific inhibitor treatment.

Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.

The gene NM_026333 slows down aging by affecting the NCX1 pathway and could be targeted for anti-aging treatments.

P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

KATP channels are important for energy balance and are targeted by drugs for diabetes, hypoglycemia, hypertension, and hair loss.

Erlotinib causes skin inflammation through IL-1, which can be reduced by anakinra.

Retinoic acid, glucocorticoids, and IGF1 increase IGFBP-3 production in human dermal papilla cells, affecting hair growth.

Exosomes could improve skin and hair treatments but are limited by cost, production difficulty, and need for more research.

Finding functions for unknown GPCRs is hard but key for making new drugs.

NKG2D gene polymorphism doesn't affect SLE risk but may influence symptoms like rash and hair loss.

PRP shows promise for treating mild alopecia areata but needs more research for cicatricial alopecias.

Notch signalling helps skin cells differentiate and prevents tumors.

Using a stimulating cream shampoo before applying Minoxidil helps it penetrate hair follicles better, enhancing its hair growth-promoting effect.

GDNF helps grow hair and heal skin wounds by acting on hair stem cells.

Two drugs, finasteride and minoxidil, are approved for hair loss treatment, but new therapies are being developed.

Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.

Gefitinib can cause skin problems, diarrhea, and nausea, but rarely causes severe lung disease or hair loss.

A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.

Hedgehog signaling in skin cells is crucial for hair growth and skin healing, but needs to be balanced to avoid harmful effects like scarring and cancer.

Scientists successfully made a human growth factor in a plant, which could help with hair growth and bone development.

CAP1 helps Arabidopsis plants grow better under ammonium stress.