5 citations
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April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” This study observed that in adult mice, a cell-autonomous size control mechanism involving the RB pathway determines the timing of S phase entry in epidermal stem cells based on their size, while external microenvironment factors influence growth rates but not this intrinsic coupling.
5 citations
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May 2013 in “Dermatologic Surgery” A direct brow lift can effectively fix nerve damage and improve appearance after surgery.
3 citations
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July 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers found that K17−/− mice suffered more severe hair follicle damage but showed reduced epidermal inflammation after ionizing radiation, with K17's absence leading to aberrant cell cycle progression due to altered p53 genome binding and reduced B-Myb degradation.
3 citations
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May 2022 in “Clinical and experimental dermatology” This review discusses potential EMT-targeting drugs for treating lichen planopilaris and emphasizes the need for clinical trials, as current evidence is limited to individual cases or case series.
3 citations
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September 2016 in “Hair transplant forum international” This abstract discusses the growing popularity of follicular unit extraction in hair restoration surgery but offers no clinical findings.
3 citations
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June 1993 in “Hair transplant forum international” This abstract reports on a presentation at a meeting that detailed the hair restoration of a patient with Norwood Class 5 pattern using 1,325 four-haired minigrafts, but it provides no clinical results.
2 citations
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January 2022 in “International Journal of Medical Sciences” In this study, kartogenin promoted hair growth by enhancing cell proliferation and migration in vitro and extended hair length in mice, suggesting its potential as a treatment for hair loss.
2 citations
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April 2021 in “International Journal of Molecular Sciences” This study found that the culture conditions, not species-specific differences, determined whether sika deer dermal papilla cells adopted a 3D spheroidal or 2D monolayer growth pattern, influencing their hair-inducing ability.
1 citations
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October 2025 in “Nature Communications” This study observed that, in mouse ear epidermal stem cells, a cell-autonomous size control mechanism involving the RB pathway dictates S phase entry timing based on cell size, despite external environmental variations affecting growth rates.
1 citations
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November 2023 in “Biomedicines” In this article, researchers link menopause to hair follicle lifecycle changes, noting that estrogen decline, metabolic shifts, genetics, and stress can contribute to hair thinning and texture variation, although effects differ among women.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this publication, independent scholar Jeffi Chao Hui Wu presents a comprehensive civilization archiving system spanning fourteen domains, highlighting innovative AGI limitations and physiological case reversals, published in ten languages and integrated into global academic infrastructures.
March 2026 in “Menopause The Journal of The North American Menopause Society” This research highlights that migraine in midlife women, during perimenopause, often becomes more frequent and intense, with evolving characteristics like migraine aura, and is associated with increased stroke risk, especially with hormone therapies.
January 2026 in “Frontiers in Pharmacology” This study found that anwuligan, an active ingredient in BaoHeWan, may promote hair regeneration in mice by activating the Wnt/β-catenin signaling pathway and enhancing hair follicle cell proliferation.
December 2025 in “PLoS ONE” In this study, among Chinese infants and young children aged 0-5 years, Type II and Type III frontal hairline patterns were the most common, with a negative correlation observed between age and hairline type.
June 2025 in “Histopathology” This study found that in superficial angiomyxomas, S100A4-positive mesenchymal niches may induce non-neoplastic adnexal epithelial growth, and highlighted evidence of mesenchymal-to-epithelial transition in eccrine duct branching, especially in Carney's complex cases.
March 2025 in “Scientific Reports” This study evaluated a menthol-based microemulsion for transdermal delivery of finasteride and silodosin, finding that it enhanced skin permeation and flux compared to aqueous solutions, suggesting a promising method for managing benign prostatic hyperplasia.
July 2024 in “Journal of Investigative Dermatology”
This pilot study found that a high fat lard diet may protect against fibrosis and affect the hair follicle cycle in a mouse model of systemic sclerosis, unlike a high fat coconut oil diet.
May 2023 in “Journal of Endocrinology and Reproduction” This study found that in primary cicatricial alopecia, reducing cholesterol production and targeting EMT modulators like PPARγ, AhR, AGTR, and TGFβ with siRNA may help mitigate hair follicle damage by modulating epithelial-mesenchymal transition, suggesting potential therapeutic strategies for slowing PCA progression.
August 2019 in “Journal of Medical Histology” This review discusses the role of epithelial mesenchymal transition (EMT) in wound healing and tissue repair, highlighting its potential contributions to progenitor cell pools, but reports no new clinical findings.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that N-acetyl-GED may protect and partially rescue human hair follicles from experimentally-induced epithelial-mesenchymal transition ex vivo, suggesting its potential in treating scarring alopecias like lichen planopilaris.
June 2017 in “Experimental and Therapeutic Medicine” In a depilated mouse model, this study found that blocking CXCL4 activity with an anti-CXCL4 monoclonal antibody promoted hair growth by inducing an earlier anagen phase, delaying hair follicle regression, and altering expression of genes and proteins related to hair growth and cell proliferation.
This study found that estradiol affects hair growth in mice by regulating the transition of hair follicles from rest to growth phases via the estrogen receptor pathway in the dermal papilla.
26 citations
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August 2008 in “Clinical endocrinology” This paper summarizes proceedings from a PCOS Special Interest Group, reporting recent advances in the understanding of PCOS follicular abnormalities, associated cardiovascular risks, and dermatological issues, but does not present new clinical findings.
24 citations
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March 2007 in “International Journal of Dermatology” This study translated and culturally adapted the Skindex-16 questionnaire into Arabic, finding it to be a reliable and valid measure of quality-of-life impacts from skin diseases in Saudi patients.
16 citations
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June 2017 in “Advances in Therapy” This review summarizes recent research on alopecia areata, highlighting advances in targeted therapies due to improved understanding of its immunopathogenesis, though it reports no new clinical results.
15 citations
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January 2017 in “Polymers” This review discusses how engineering cell surfaces with polyelectrolytes can address challenges in cell therapy and related biomedical fields and reports no new research findings.
14 citations
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January 2015 in “Genetics and molecular research” This study found that numerous genes involved in hair growth, including 73 co-up-regulated ones, were differentially expressed in goat hair follicles during the hair growth cycle.
13 citations
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January 2017 in “Experimental Dermatology” This editorial reviews recent advances in the mechanisms and translation of wound healing but provides no new research findings.
9 citations
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March 2011 in “Current Pharmaceutical Biotechnology” This review discusses current stem cell technologies, their potential therapeutic uses, and imaging techniques for tracking transplanted cells, without reporting new experimental results.