18 citations,
January 2008 in “Journal of The American Academy of Dermatology” Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.
375 citations,
February 2006 in “Journal of Cell Science” The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.
103 citations,
January 2006 in “Journal of Cell Science” The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.
7 citations,
July 2019 in “International Journal of Molecular Sciences” PGA-4HGF may help treat hair loss by activating hair growth pathways and extending the hair growth phase.
25 citations,
October 2018 in “PloS one” Key genes regulate hair follicle phase changes in Inner Mongolia cashmere goats.
January 2019 in “Applied Organometallic Chemistry” The compound (NH4)2Mn0.17Cu0.83Cl4.2H₂O has a specific structure, shows weak magnetism at low temperatures, and undergoes phase changes at high temperatures.
62 citations,
November 2016 in “Nanoscale” Medium to larger nanogels effectively deliver drugs through hair follicles when heated.
8 citations,
April 2020 in “Journal of Ethnopharmacology” Herbs might help with hair loss, but more research is needed to confirm their safety and effectiveness.
7 citations,
March 2019 in “Journal of cosmetic dermatology” African hair has the most lipids, while Caucasian hair is more hydrated and stronger.
87 citations,
April 2018 in “Biochemical and Biophysical Research Communications” Exosomes from dermal papilla cells can help grow hair and might treat hair loss.
71 citations,
January 2015 in “Journal of molecular cell biology/Journal of Molecular Cell Biology” mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.
25 citations,
August 2010 in “Journal of Biological Chemistry” Nuclear Factor I-C is important for controlling hair growth by affecting the TGF-β1 pathway.
1 citations,
September 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” MicroRNA-148a is crucial for maintaining healthy skin and hair growth by affecting stem cell functions.
33 citations,
September 2017 in “Molecules” Red ginseng oil and its components help promote hair regrowth and could treat hair loss.
24 citations,
October 2017 in “Scientific reports” Changing light exposure can affect hair growth timing in goats, possibly due to a key gene, CSDC2.
13 citations,
November 2022 in “Biomaterials Science” The microneedle patch effectively promotes hair regrowth by delivering miR-218.
9 citations,
January 2015 in “Fundamental & clinical pharmacology” Cyclosporine A helps hair grow by blocking a process that would otherwise cause hair cells to die.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” A PTH-based treatment improved hair regrowth better than ruxolitinib in a mouse model of hair loss.
24 citations,
June 2018 in “Expert Review of Pharmacoeconomics & Outcomes Research” Microneedle technology is beneficial for drug delivery and could make vaccinations cheaper and more accessible.
February 2024 in “Cancers” New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.
14 citations,
May 2008 in “Journal of proteome research” Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.
April 2019 in “Biometrics” The new clinical trial design is promising but needs real-world trials to test its effectiveness and possible enhancements.
13 citations,
March 2020 in “Genes” Disrupting the FGF5 gene in rabbits leads to longer hair by extending the hair growth phase.
33 citations,
June 2007 in “International Journal of Pharmaceutics” The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.
14 citations,
January 2009 in “Experimental Dermatology” Hair sheds gradually from the follicle, with readiness to shed indicated by less attachment material.
12 citations,
September 2018 in “Journal of Drug Delivery Science and Technology” The silk fibroin hydrogel with FGF-2-liposome can potentially treat hair loss in mice.
10 citations,
May 2020 in “Dermatology Research and Practice” Proteoglycans are important for hair growth, and a specific treatment can help reduce hair loss.
1 citations,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
41 citations,
July 2015 in “Current Drug Discovery Technologies” Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.
39 citations,
December 2001 in “JNCI: Journal of the National Cancer Institute” Using a gene therapy with the Sonic Hedgehog gene helps mice regrow hair faster after losing it from chemotherapy.