December 2014 in “Research and Reviews: Journal of Pharmacology and Toxicological Studies” This study found that applying pet ether extract of Brassica oleracea to rats' skin promoted earlier and longer anagen phases in hair growth, outperforming 1% minoxidil.
January 1999 in “Journal of S C C J” This study found that STAT3 signaling is essential for initiating the hair growth phase but not involved in hair follicle development during the fetal period.
September 2004 in “PubMed” This article describes the development and growth stages of hair follicles during intrauterine life and subsequent growth phases on the scalp but reports no new clinical results.
8 citations
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September 2024 in “BMC Genomics” In this study, researchers found that the novel gene circCFAP20DC enhances the proliferation of goat follicular granulosa cells by activating the RB pathway, facilitating their progression from the G1 to S phase during follicular development.
170 citations
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September 2019 in “Evidence-based Complementary and Alternative Medicine” This review discusses the use of 36 medicinal plant species for cutaneous wound healing and reports no new clinical results; the authors highlight the potential for these traditional practices to inform modern therapies.
9 citations
,
January 2021 in “Biomolecules” This study demonstrates the potential of infrared spectral imaging to assess hair follicle structures and heparan sulfate proteoglycan distribution across different phases of the hair growth cycle, offering promise for alopecia research.
4 citations
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January 1981 in “PubMed” This study found that medullary cell content in mammal hair evolves from an amorphous form to a biphasic phase, with human and anthropoid hair containing both macrofibrils and microfibrils.
July 2025 in “Journal of Integrated Health Sciences” In this study, a 32-year-old female with alopecia areata experienced significant symptom relief after receiving traditional Ayurvedic treatments, including Virechana, Pracchana, and Rasayana therapies, alongside external application of Chakramarda. The protocol was reported to be simple, cost-effective, and highly efficacious.
January 2025 in “Journal of Ethnopharmacology” This study found that external application of DGD activates the Wnt/β-catenin signaling pathway, promoting hair follicle anagen phase entry, and is a more effective and safer treatment for androgenetic alopecia in mice compared to oral administration.
July 2023 in “IntechOpen eBooks” This review highlights that alopecia areata, a common type of hair loss, currently lacks preventive or curative treatments, and traditional therapies such as minoxidil and corticosteroids offer inconsistent results, necessitating patient-consensual treatment planning.
June 2023 in “The journal of sexual medicine” This case report describes a 10-year multidisciplinary treatment of a transgender woman in Slovenia, reporting a successful medical and social transition with stable emotional health, abstinence from alcohol, and no regrets following her transition.
March 2016 in “Experimental Dermatology” This study reported that EGFR activation leads to suppression of Stathmin, which may promote synchronized entry into catagen in hair follicles, highlighting potential mechanisms involving EGFR in hair cycle transitions.
1 citations
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February 2022 in “Clinical, Cosmetic and Investigational Dermatology” In this study, researchers found that the thyroxine receptor agonist TDM10842 accelerated the onset of anagen, a hair growth phase, in C3H mice, potentially through activation of the Wnt/beta-catenin and Hedgehog pathways, with Pclaf playing a key role in this process.
February 2024 in “Cancers” This review highlights recent progress in developing androgen receptor degraders, such as PROTACs, for treating castration-resistant prostate cancer, and notes that several have entered phase I or II clinical trials, showcasing potential to address drug resistance challenges.
January 2019 in “Applied Organometallic Chemistry” The compound (NH4)2Mn0.17Cu0.83Cl4.2H₂O has a specific structure, shows weak magnetism at low temperatures, and undergoes phase changes at high temperatures.
50 citations
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June 1999 in “Annals of Oncology” This study found that long-term weekly administration of docetaxel is feasible at doses up to 45 mg/m² per week with acceptable toxicity, and suggests further evaluation with 40 mg/m² for phase II studies.
9 citations
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December 2021 in “Molecules” This study found that certain metabolites from the plants Bidens pilosa, Calophyllum inophyllum, and Fagraea berteroana may support hair follicle growth by promoting dermal papilla cell proliferation, supporting their traditional use in hair care.
8 citations
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May 2017 in “Chinese Journal of Integrative Medicine” Among in vitro and in vivo models, this study found that Miscanthus sinensis var. purpurascens flower extract may promote hair growth, potentially by modulating growth factor expressions and facilitating earlier hair follicle transitions in treated mice.
3 citations
,
March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study introduced Neurospectrum, a framework that effectively identifies meaningful neural dynamics by encoding neural activity into latent trajectories, and reported that it outperformed traditional methods in tracking synchronization, reconstructing stimuli, and identifying fMRI biomarkers in various datasets.
3 citations
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January 2023 in “Journal of Pharmaceutical Negative Results” This study reports that fluconazole emulgel formulations, using jojoba oil and liquid paraffin, showed effective drug release and improved characteristics for treating skin diseases compared to traditional oral formulations.
January 2026 in “Cosmetics” In this study, yeast fermentation of Platycladus orientalis leaves was shown to enhance hair growth-promoting properties by affecting cell cycle phases in human dermal papilla cells, increasing growth factor VEGF, reducing inflammatory factor TGF-β1, and altering the expression of Wnt/β-catenin pathway-related genes.
December 2025 in “International Journal of Innovative Technologies in Social Science” This systematic review concluded that oral JAK inhibitors, such as baricitinib and deuruxolitinib, are effective and generally well-tolerated treatments for moderate-to-severe alopecia areata, offering advantages over traditional therapies.
August 2025 in “Rare Metals” In this study, carbon dots derived from metformin and dopamine (MD‐CDs) effectively promoted healing in bacterial-infected wounds by inhibiting infection, expediting inflammation-to-healing transition, enhancing cell proliferation and migration, and fostering collagen deposition and hair follicle regeneration.
This study found that ocu-miR-205 promotes the apoptosis of dermal papilla cells and the transformation of hair follicles from growth to regression and resting phases in Rex rabbits.
This study found that ocu-miR-205 influences hair follicle density in Rex rabbits by promoting dermal papilla cell apoptosis and transforming hair follicles from growth to resting phases through signaling pathway modulation.
8 citations
,
August 2025 in “Journal of Translational Medicine” This comprehensive review suggests that CD44 signaling plays a significant role in post-natal skin wound healing and scar formation, with potential for therapeutic approaches targeting CD44 to shift from fibrotic scarring towards regenerative healing, including wound regeneration and hair neogenesis.
July 2024 in “Journal of Investigative Dermatology” Human epidermal stem cells divide faster than previously thought.
September 2025 in “Stem Cells Translational Medicine” This study found that exosomes from human umbilical cord stem cells, pretreated with lithium chloride, significantly enhance hair regeneration in mice by activating the Wnt signaling pathway through miR-146a-5p.
3 citations
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February 2016 in “Nature Biotechnology” New drug shows promise for better hair growth in baldness treatment.
34 citations
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March 2001 in “Cleveland Clinic Journal of Medicine” This article reviews the triggers, diagnosis, and management of telogen effluvium in men and women, emphasizing the role of patient education and reassurance, but presents no new clinical findings.