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c-kit affects hair growth and color in alopecia areata and androgenetic alopecia.

The drug BAY 1158061 is safe, well-tolerated, and shows potential for treating diseases related to prolactin.

Certain gene variations and irregular X chromosome activity may contribute to hair loss in women who can have children.

Bicalutamide may be a promising alternative treatment for female pattern hair loss.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.

Malnutrition can cause unusual eyelash growth and hair loss.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Mutations in certain receptors can cause diseases and offer new treatment options.

Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

Removing the ROBO4 gene in mice reduces skin inflammation and hair loss by affecting certain inflammation pathways and gene expression.

17β-estradiol may help hair growth by increasing cannabinoid receptor type 1.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Memantine may slightly improve memory in people with Down syndrome, but more research is needed.

Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

COVID-19 can cause various skin lesions, which may result from the virus and immune response, and are not directly linked to illness severity.

Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.

The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.

Tirzepatide might help manage PCOS in obese patients but needs more research to confirm safety and effectiveness.

MR antagonists may improve skin health and wound healing, especially in aging.

Gene therapy helped rats with a specific type of rickets grow hair without severe inflammation.

Hormonal treatments can improve acne, but they come with potential side effects and risks.

The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.

ERG increases SOX9, promoting prostate cancer growth and invasion.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.