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Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

Skin stem cells can help improve skin repair and regeneration.

A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.

Mitochondria may influence how cells respond to radiation, affecting nearby non-irradiated cells.

The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.

Lactate production is important for activating hair growth stem cells.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.

Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.

The method increases stem-like cells for better skin regeneration.

Vesicles from irradiated mouse cheek skin help cells survive radiation.

Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.

Hair growth-related cells need the enzyme SCD1 to help maintain the area that supports hair growth.

Hair follicle stem cells in hairpoor mice are disrupted, causing hair loss.

KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.

Inactive hair follicle stem cells help prevent skin cancer.

Scientists made working hair follicles using stem cells, helping future hair loss treatments.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.

miR-133a-3p and miR-145-5p help goat hair follicle stem cells differentiate by controlling NANOG and SOX9.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

After skin injury, adult mice can grow new hair follicles, and this process can be increased or stopped by manipulating Wnt signals.

Hair follicle stem cells can form both hair follicles and skin.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

Removing β-catenin in certain stem cells causes hair whitening and pigmentation issues.