research Trichohyalin, an Intermediate Filament-Associated Protein of the Hair Follicle
Trichohyalin is a protein in hair follicles that helps form hair filaments.
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240-270 / 361 resultsresearch Hairless Suppresses Vitamin D Receptor Transactivation in Human Keratinocytes
Hairless protein can block vitamin D activation in skin cells.
research Human Hair Shaft Proteomic Profiling: Individual Differences, Site Specificity, And Cuticle Analysis
Human hair proteins vary by individual, body site, and ethnicity, useful for forensics.
research Delayed Epidermal Permeability Barrier Formation and Hair Follicle Aberrations in Inv-Cldn6 Mice
Mice with too much Claudin-6 have skin barrier problems and abnormal hair growth.
research Formation of the Iε-(γ-Glutamyl)Lysine Crosslink in Hair Proteins: Investigation of Transamidases in Hair Follicles
Transamidases help form strong crosslinks in hair proteins, crucial for hair strength.
research Vitamin D And Skin Diseases: A Review
Vitamin D is important for skin health and can help treat psoriasis, atopic dermatitis, and vitiligo.
research Disorders of Keratinization
Understanding genetic mutations helps diagnose and treat skin disorders like ichthyosis.
research Proliferation and Differentiation of Cultured Human Keratinocytes Is Modulated by 1,25-Dihydroxyvitamin D3 and Synthetic Vitamin D3 Analogues in a Cell Density-, Calcium-, and Serum-Dependent Manner
Vitamin D3 and its analogues affect skin cell growth and development depending on cell density, calcium levels, and serum presence.
research Vitamin A Toxicity: When One a Day Doesn't Keep the Doctor Away
Vitamin A toxicity can cause severe health issues and may require a liver transplant if other treatments fail.
research New Developments in the Molecular Treatment of Ichthyosis: Review of the Literature
New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.
research p53 Is a Direct Transcriptional Repressor of Keratin 17: Lessons from a Rat Model of Radiation Dermatitis
The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.
research Efficient In Vitro Transfection of Human Keratinocytes with an Adenovirus-Enhanced Receptor-Mediated System
The AVET system effectively delivers genes to human keratinocytes and may help treat skin diseases.
research Identification of the C-Terminal Tail Domain of AHF/Trichohyalin as the Critical Site for Modulation of the Keratin Filamentous Meshwork in the Keratinocyte
The C-terminal tail of AHF/trichohyalin is essential for organizing keratin filaments in keratinocytes.
research Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes
A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.
research Location of Keratin-Associated Proteins in Developing Fiber Cuticle Cells Using Immunoelectron Microscopy
Keratin-associated proteins are part of the developing hair fiber cuticle.
research NIPAL4 Deletion Identified in an American Bully with Autosomal Recessive Congenital Ichthyosis and Response to Topical Therapy
An American Bully with a genetic skin condition improved significantly with specific topical treatments.
research Plasma-Polymerized Antibacterial Coating of Ovine Tendon Collagen Type I Crosslinked with Genipin and Dehydrothermal-Crosslinked as a Cutaneous Substitute for Wound Healing
The GNP crosslinked scaffold with antibacterial coating is effective for rapid wound healing and infection prevention.
research Alopecia as the Presenting Symptom of Syphilis
Hair loss can be a symptom of syphilis.
research Generation of iPS-Derived Model Cells for Analyses of Hair Shaft Differentiation
Researchers created a mouse cell line to study hair growth and test hair growth drugs.
research First Symposium of Ichthyosis Experts
Experts met to improve care for ichthyosis patients in Spain.
research Laccase-Catalyzed Poly(Tyrosine) Grafting Improves The Performance Of Wool
Using laccase to add poly(tyrosine) to wool makes it less likely to shrink and stronger.
research Qu-Shi-Yu-Fa Decoction Promotes Hair Cycle and Keratinization by Upregulating Foxn1 and Tgm3 to Treat Androgenetic Alopecia
Qu-shi-yu-fa Decoction may help treat hair loss by promoting hair growth and strengthening hair follicles.
research Characterization of Hair Lipid and Protein Dynamics Using EPR Spectroscopy and Treatment Effects
Hair treatments and dehydration affect hair's lipid and protein behavior, influencing its flexibility and appearance.
research Enzymatic Crosslinking of Amino Acids Improves the Repair Effect of Keratin on Hair Fiber
Using enzymes to link proteins makes hair repair treatments more effective and long-lasting.
research Collodion Baby to Bathing Suit Ichthyosis: A 6-Year Follow-Up
A baby with a skin condition improved with treatment but developed a rare form of the condition affecting only his trunk.
research Viva Questions from the Indian Journal of Dermatology, Venereology, and Leprology
The document concludes that various skin conditions have specific characteristics and treatments, and highlights the importance of vitamin D in managing these dermatological issues.
research Cross-Linked Features of Mouse Pelage Hair Resistant to Detergent Extraction
Two mouse mutants have defective hair cuticle cross-linking.
research Wnt/β-Catenin Signaling: Function, Biological Mechanisms, and Therapeutic Opportunities
The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
research Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases
More precise, personalized therapies are needed for autoimmune diseases.
research The Expanding Significance of Keratin Intermediate Filaments in Normal and Diseased Epithelia
Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.