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This study observed that COX-2 overexpression in transgenic mice led to a significant reduction in skin tumor development compared to controls, challenging the expected role of COX-2 in promoting tumors.

This study found that overexpression of PKCepsilon in transgenic mice reduced papilloma development but accelerated carcinoma formation in a skin tumor promotion model.

This study found that dimethylarsinic acid significantly accelerates skin tumor development in hair follicle-targeted K6/ODC transgenic mice.

This study observed that targeted expression of the neu oncogene in transgenic mice led to significant epidermal hyperplasia and a carcinoma-like appearance, suggesting a crucial role for erbB2 signaling in epidermal proliferation and carcinogenesis.

This study demonstrated that a specific 9-kbp fragment of the bovine keratin 6 gene effectively directs tissue-specific and inducible expression in transgenic mice, suggesting potential applications for targeted gene therapy in hyperproliferative skin conditions.

This study found that oral estradiol was generally effective in achieving target 17-β estradiol levels in transgender women, but often failed to suppress testosterone adequately, with variability in individual responses.

This study suggests that the HCR risk allele within the PSORS1 locus may contribute to psoriasis susceptibility by altering gene expression related to skin structure and differentiation, although these changes alone might not result in clinical symptoms.

This review discusses the long-term effects of gender affirming hormone therapy and reports no new clinical findings, recommending a shared decision-making approach to balance benefits and risks for transgender individuals.

This review discusses the dermatologic needs and care considerations for transgender patients undergoing gender transition, highlighting the unique role dermatologists can play, but it does not report new clinical results.

This research identified that the constitutive and inducible expression of the Keratin 6 gene in transgenic mice skin is controlled by multiple regulatory elements spread throughout its 5' flanking region.

This article addresses the complexity of treating acne in female-to-male transgender adolescents undergoing testosterone therapy, highlighting concerns about co-administered treatments and their potential risks.

In this case report, a transgender woman experienced scalp hair regrowth after approximately six months of oral estradiol and spironolactone treatment, achieving testosterone levels within the normal female range.

This study observed that overexpression of the enzyme ODC in transgenic mice caused hair loss and skin changes similar to human papular atrichia, suggesting that ODC might be involved in a critical hair follicle function pathway.

This paper reviews the evolution and classification of forehead reduction and orbital contouring techniques in transgender females, but reports no new clinical findings.

This study reports that the transgenic expression of Dsg1 in mice rescued the severe B6-Dsg3−/− phenotype and created a syngeneic mouse model of pemphigus vulgaris, which may aid in understanding autoimmunity mechanisms.

This review suggests that oocyte retrieval may be viable for transgender men on testosterone therapy, with potentially manageable effects on fertility preservation without requiring extensive hormone suspension.

This research explored methods to obtain transgenic sheep embryos expressing synthetic spider silk genes in hair follicles using somatic cell nuclear transfer, with successful in-vitro development observed.

This source outlines what it takes to be a competent provider for transgender individuals, focusing on their health needs, disparities, and coverage, and examines medical biases and hormone treatment guidelines, alongside treatment options for different age groups, concluding with evolving trends in medical education.

Transgender women can still get testicular cancer, so proper screening is important.

This review discusses hair restoration procedures for transgender patients undergoing gender transformation surgery and describes the authors' surgical approach but reports no clinical outcomes.

This study found that the incidence of hyperkalemia is low among transgender, gender nonbinary, and gender-nonconforming individuals, particularly those under 45, but increases with age.

This study found that among MtF transgender individuals, those with early-onset gender dysphoria exhibited differences in age at surgery, sexual orientation, and sexual activity compared to those with later-onset dysphoria.

This study found that transgender men using testosterone therapy had higher rates of acne and increased body hair growth, resembling male patterns more closely than those not on testosterone.

This study found that minoxidil increases the expression of a reporter gene linked to hair growth in cultured hair follicles from transgenic mice, suggesting a potential model for studying hair biology.

Ensure respectful and inclusive care for transgender and gender-diverse patients during surgery.

In this retrospective cohort study, researchers found that persistent discontinuation of gender-affirming hormones among transgender adolescents was rare, mainly due to achieving gender expression goals or access issues, with very few reidentifying with their birth-assigned sex.

This review outlines the existing literature on gender-affirming hormone therapy and cancer risk among transgender populations but offers no new clinical findings, highlighting the need for more research to address cancer health disparities.

In this study, researchers found that hTERT/SV40 immortalization of human dermal fibroblasts up-regulates skin cell markers and highlights the SIRT1 and miR-93 pathways' roles in maintaining fibroblast proliferation, potentially benefiting developments in the cosmetic industry.

This source suggests that migraine prevalence increases in transgender women using oestrogen and decreases in transgender men using testosterone, with high oral oestrogen doses in transgender women potentially linked to aura risk.

This review discusses the emerging considerations and challenges of uterus transplantation for transgender women but presents no new clinical results.