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Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.

In 2021, JAMA Dermatology published significant findings on skin conditions post-COVID vaccination, melanoma surveillance, atopic dermatitis treatments, and confirmed that sun protection does not harm bone health.

Men and women react differently to opioids, with hormones potentially influencing these differences.

Increased free testosterone can lead to stronger bones and less body fat but also higher risks of prostate cancer, hair loss, spine issues, and high blood pressure.

Advancements in tissue engineering show promise for hair follicle regeneration to treat hair loss.

Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.

The document concludes that while "hair follicle cloning" shows promise for unlimited donor hair, it faces challenges with consistency and safety in humans.

Growing human skin cells in a 3D environment can stimulate new hair growth.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

Larger spheroids improve hair growth, but size doesn't guarantee thicker hair.

Hair follicle regeneration possible, more research needed.

Researchers developed a method to grow hair follicle cells for transplantation using a special chip.

The place where hair is transplanted can affect its growth and survival rates.

PL-FUT is an effective hair restoration method for burn victims with minimal scarring and high patient satisfaction.

New hair transplant method allows for hair regrowth in the donor area and less scarring.

Transplanted transected hair follicles can survive but grow at unsatisfactory rates and are thinner, suggesting limited potential for unlimited donor hair supply.

The book is a valuable, comprehensive guide on hair transplantation, recommended for surgeons and students, with minor areas for improvement.

Cutting hair follicles into pieces for transplantation results in poor growth and thinner hair, and the technique is more invasive than previously thought.

The recipient site can affect the growth and survival of transplanted hair but not its thickness.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Androgens can both increase and decrease hair growth in different parts of the body.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.