research Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organs
Sox21 is crucial for tooth development and enamel formation by preventing cells from changing into a different type.
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research Defining the Localization and Molecular Characteristics of Minor Salivary Gland Label-Retaining Cells
The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.
research Epidermal Expression of the Truncated Prelamin A Causing Hutchinson-Gilford Progeria Syndrome: Effects on Keratinocytes, Hair, and Skin
Progerin affects cell shape but not hair or skin in mice.
research Evaluation of the Efficacy and Safety of Topical Procyanidin B2 and Placebo in the Treatment of Androgenetic Alopecia in Men: A Randomized, Double-Blind, Placebo-Controlled Study
Topical procyanidin B2 significantly increases hair count and is a safe treatment for male pattern baldness.
research Regeneration of Dermis: Scarring and Cells Involved
Different fibroblasts play key roles in skin healing and scarring.
research Female Pattern Hair Loss: A Clinical and Pathophysiological Review
Female Pattern Hair Loss affects women's self-esteem and needs more research for better treatment.
research Platelet-Rich Plasma: The Journey So Far
Platelet-rich plasma shows potential for hair loss and skin rejuvenation but needs more research for widespread use.
research Cellular Senescence in Tissue Repair: Every Cloud Has a Silver Lining
Cell aging can be both good and bad for tissue repair.
research Scalp Psoriasis: Alopecia and Treatment Challenges
Scalp psoriasis can cause different types of hair loss, with some patients developing permanent hair loss, and treatment may be stopped due to skin reactions.
research Hedgehog Pathway Inhibitors Against Tumor Microenvironment
Hedgehog pathway inhibitors can treat certain aggressive cancers but face limitations like resistance and side effects.
research Distinct Phenotypic and Genomic Signatures Underlie Contrasting Pathogenic Potential of Staphylococcus Epidermidis Clonal Lineages
Staphylococcus epidermidis A/C strains are more antibiotic-resistant and infection-adapted, while B strains thrive in hair follicles.
research An Appraisal of Laboratory Models of Androgenetic Alopecia: A Systematic Review
Better hair loss models needed for research.
research Skin Cell-Derived Extracellular Vesicles: A Promising Therapeutic Strategy for Cutaneous Injury
Skin cell-derived vesicles can help heal skin injuries effectively.
research Innate Immunity and the Regulation and Mobilization of Keratinocyte Stem Cells: Are the Old Players Playing a New Game?
Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.
research Wound Healing in Development: Mechanisms and Regulation
Wounds heal without scarring in early development but later result in scars, and studying Wnt signaling could help control scarring.
research An Updated Etiology of Hair Loss and the New Cosmeceutical Paradigm in Therapy: Clearing the Big Eight Strikes
New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.
research Progenitor Cell Dysfunctions Underlie Some Diabetic Complications
Diabetes causes lasting cell dysfunctions, leading to serious complications even after blood sugar is controlled.
research Bio-Pulsed Stimulation Effectively Improves the Production of Avian Mesenchymal Stem Cell-Derived Extracellular Vesicles That Enhance the Bioactivity of Skin Fibroblasts and Hair Follicle Cells
Bio-pulsed stimulation increases production of beneficial vesicles from bird stem cells that improve skin and hair cell functions.
research Modeling of Solar UV-Induced Photodamage on the Hair Follicles in Human Skin Organoids
Sunlight exposure damages hair follicles, but certain stem cell-derived particles can reduce this damage and help with hair regeneration.
research Innovative Use of Spironolactone as an Antiandrogen in the Treatment of Female Pattern Hair Loss
Spironolactone helps regrow hair in women with hair loss.
research MicroRNA-21 in Skin Fibrosis: Potential for Diagnosis and Treatment
MicroRNA-21 could help diagnose and treat skin fibrosis.
research The GPI-Anchored Protein Thy-1/CD90 Promotes Wound Healing by Enhancing Skin Perfusion
Thy-1 protein helps improve blood flow and wound healing in the skin.
research Pathological Sequelae of Long-Haul COVID
Long-haul COVID can cause lasting symptoms affecting many body systems and may be linked to ongoing inflammation and immune system issues.
research Interventions for Morphea
Some treatments like methotrexate with prednisone might help juvenile morphea, but more research is needed to confirm.
research Managing Patterned Hair Loss – A Hair Raising Task!
Hair loss can be managed with treatments like minoxidil, finasteride, and others, but there are still gaps in effectiveness and off-label usage is increasing.
research Current Aspects of Polycystic Ovary Syndrome: A Literature Review
Polycystic ovary syndrome is a common hormonal disorder in women, linked to increased risk of metabolic and heart diseases, and needs more research for better understanding and treatment.
research A Nude Mouse Model of Hypertrophic Scar Shows Morphologic and Histologic Characteristics of Human Hypertrophic Scar
Nude mice with grafted human skin developed scars similar to human hypertrophic scars.
research The Non-Neuronal and Nonmuscular Effects of Botulinum Toxin: An Opportunity for a Deadly Molecule to Treat Disease in the Skin and Beyond
Botulinum toxin has potential for treating various skin conditions and improving wound healing.
research The Promise and Challenges of Cell Therapy for Psoriasis
Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.
research A Review of the Evidence for and Against a Role for Mast Cells in Cutaneous Scarring and Fibrosis
Mast cells likely promote skin scarring and fibrosis, but their exact role is still unclear.