October 2023 in “Frontiers in endocrinology” Effective PCOS treatments require targeting specific signaling pathways.
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
Dermal stem cells help regenerate hair follicles and heal skin wounds.
286 citations,
June 2012 in “Nature Immunology” Hair follicles help attract immune cells to the skin during stress.
9 citations,
July 2022 in “Cell reports” Sox2 controls hair color by affecting pigment production in hair follicles.
29 citations,
June 2020 in “International Journal of Molecular Sciences” Notch signaling disruptions can cause various skin diseases.
2 citations,
November 2023 in “Biomolecules” WNT signaling is crucial for skin development and healing.
2 citations,
May 2022 in “Diagnostics” Vitamin D levels in hair don't match those in blood, so hair isn't a reliable indicator of Vitamin D status.
40 citations,
March 2022 in “Small” Hydrogel with M2-derived exosomes improves wound healing by slowly releasing exosomes that help reduce inflammation and promote tissue repair.
34 citations,
January 2013 in “Frontiers in genetics” Stem cells can help other stem cells by producing supportive factors.
21 citations,
September 2008 in “Magnetic Resonance Imaging” MRI can effectively image skin structures noninvasively.
14 citations,
October 2000 in “Genomics” Rat dermal papilla cells have unique genes crucial for hair growth.
9 citations,
August 2022 in “Frontiers in Pharmacology” Kangfuxin (KFX) extract speeds up wound healing and improves skin regeneration.
2 citations,
September 2023 in “International journal of molecular sciences” Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.
April 2024 in “Journal of translational medicine” Melanocytes are important for normal body functions and have potential uses in regenerative medicine and disease treatment.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Scarred skin in lichen planopilaris loses immune cells due to a decrease in a specific protein in skin cells.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Human hair follicles have a unique way of using energy and might use the Cori cycle; blocking CCR5 could help treat hair loss.
40 citations,
January 2013 in “Journal of Korean Medical Science” Iron deficiency may contribute to hair loss.
13 citations,
January 2020 in “Scientific Reports” The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
61 citations,
April 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.
43 citations,
February 2019 in “International immunology” Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.
13 citations,
January 2018 in “Cellular Physiology and Biochemistry” Fat-derived stem cells can help protect and repair skin stem cells from aging caused by UV light.
8 citations,
July 2014 in “General and Comparative Endocrinology” Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.
280 citations,
July 2018 in “Antioxidants” Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.
65 citations,
November 2012 in “Tissue Engineering Part B-reviews” Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.
39 citations,
April 2020 in “IntechOpen eBooks” Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
25 citations,
June 2018 in “Journal of The American Academy of Dermatology” Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.
10 citations,
June 2018 in “Journal of visualized experiments” The document concludes that the technique allows for the detection of LDH activity in various tissues, showing where cells are actively metabolizing glucose.
8 citations,
July 2017 in “Biochemical and biophysical research communications” A new compound, BOI, can help hair grow by changing hair cycle phases and increasing certain cell contents.
3 citations,
January 2024 in “Signal transduction and targeted therapy” Lymphatic vessels are essential for health and can be targeted to treat various diseases.