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This study found that human skin with hair follicles and sebaceous glands absorbed significantly more steroids than scar skin without these appendages, indicating their role in steroid penetration.

This study found that UVA and UVB exposure increased hydroquinone and sunscreen absorption in nude mouse skin, with less absorption enhancement observed in more lipophilic sunscreens.

In this study, brief ultrasound exposure reduced the follicular contribution to hydrocortisone absorption while significantly increasing total skin permeability, likely due to removal of the upper stratum corneum.

This study found that ketorolac tert-butyl ester enhances skin permeation and follicular absorption compared to ketorolac, highlighting the role of lipophilicity and solubility in prodrug design.

This study found that osthole, a coumarin derivative, demonstrated significantly higher skin accumulation and potential skin irritation compared to coumarin, which showed negligible alterations in protein biomarkers.

This article includes summaries of multiple studies on dermatological topics like Imiquimod's effects on tumors, vitamin C absorption enhancement, and ferritin levels in hair loss, but reports no new results itself.

This study investigated the use of dissolving microneedle patches to improve the skin-lightening effects of alpha-arbutin and resveratrol, finding that the patches enhanced intradermal delivery and slightly decreased the melanin index without affecting skin hydration or causing irritation over 24 hours.

In this study, different treatments on ex vivo skin models effectively simulated varying levels of skin damage, demonstrating the value of these models in testing skin repair products and studying how a compromised skin barrier affects viral penetration.

This review summarizes current knowledge on tight junctions in mammalian skin and their role in drug delivery and interaction with other barrier components, but reports no new experimental results.

This study found that ultraviolet radiation negatively affects hair follicle functions in human scalp skin, and caffeine application may provide some protective effects against this damage.

This study found that coadministering minoxidil with tretinoin cream increased minoxidil absorption nearly threefold in healthy males, attributed to increased stratum corneum permeability.

This study found that using an electrical microneedling device enhanced the penetration of liposomal melanin-fluorescein into hair structures and widened the follicular infundibulum in ex vivo human skin models.

This review discusses various nanoparticles used to enhance skin permeation and target delivery to skin organelles, but reports no new experimental results.

This review reports on the dual aspect of fullerene in skincare, highlighting its beneficial antioxidant properties as well as potential toxicity and skin cell reactions, while identifying areas for future research.

This review discusses various strategies to enhance drug delivery through the skin barrier, highlighting liposomes as promising carriers for increased dermal concentrations in topical therapies, but reports no new research results.

This study found that hair follicles contribute significantly to caffeine absorption shortly after topical application, with a faster absorption rate compared to the stratum corneum.

This article discusses the role of stratum corneum disruption in dandruff and suggests that treatments improving scalp barrier integrity along with antifungal activity may be beneficial; it reports no new research findings.

This study found that nanostructured lipid carriers with clobetasol propionate significantly enhance follicular drug delivery compared to commercial cream, and manual massage further doubles follicular retention.

This study found that biologically synthesized silver nanoparticle gel demonstrated excellent wound healing efficacy in rats, surpassing both marketed formulations and ionic silver.

This review highlights the need for methodologies to understand and quantify drug penetration into hair follicles as significant drug pathways, noting this area lacks comprehensive articles and reports no new results.

This study found that the HPCH-based formulation P-08–016 may facilitate finasteride deposition in the dermis, potentially offering an alternative to systemic therapy by minimizing systemic absorption.

In this study, extracting internal lipids from Caucasian hair fibers led to decreased water permeability, influenced by the fluidity of lipids.

This review examines non-invasive methods for diagnosing inflammatory skin diseases like lupus erythematosus and psoriatic inflammation using samples from plucked hair and skin tape-strips, but no new clinical results are presented.

This study reported that the compound (1R, 2S)-4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile effectively stimulated hair growth in mice and reduced sebum production in hamsters.

Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.

Light and temperature affect the daily skin function rhythms in hairless rats, with temperature influencing water loss but not skin hydration.

Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.

In this case report, researchers documented a rare instance of trans-epidermal elimination of insulin formulation in a 45-year-old woman with diabetes, suggesting that insulin or its excipients may have caused a granulomatous reaction leading to skin lesions at injection sites and impaired diabetes control.

In this study, researchers developed topical tofacitinib-loaded cationic lipid nanoparticles, which improved absorption and targeted hair follicles in an ex vivo pig ear model, showing promise in treating alopecia areata by reducing symptoms through the JAK/STAT pathway.

This article reviews EU cosmetic product claim regulations and highlights increased harmonization and enforcement while reporting no new results.