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Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

Some birth control pills have a higher risk of blood clots than others.

Excipients greatly affect how well curcumin nanocrystals penetrate the skin and target hair follicles.

The formulated gel is a promising treatment for alopecia areata.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

Acne treatment varies, with topical and systemic therapies effective, and more research needed on treatment order and long-term effects.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.

People often struggle to consistently use contraceptives and other medications, and long-acting options might be better for those who want to avoid daily doses.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

NTF gel improves finasteride delivery for hair loss treatment, reducing side effects.

Women have a higher risk of blood clots from hormonal factors and need careful treatment, especially during pregnancy.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Nanoemulsions with minoxidil and clove oil effectively target hair follicles for better alopecia treatment.

The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.

Many adults in Porto have acne, but few know or treat it.

A small number of premenopausal female blood donors had high prolactin levels, often due to stress, and retesting is recommended to prevent misdiagnosis.

The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.

A combination of nanomilled oral testosterone and dutasteride normalized testosterone levels in men with low testosterone and is safe for short-term use.