151 citations,
November 2018 in “International Journal of Pharmaceutics” Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
67 citations,
January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
Labrasol® in phospholipid vesicles improves minoxidil delivery to the skin, potentially aiding hair growth treatments.
January 2025 in “AAPS PharmSciTech” Transethosomes improve drug delivery through the skin and show promise for treating various conditions.
February 2023 in “Materials today bio” The treatment effectively promotes hair regrowth in androgenetic alopecia without causing skin irritation.
October 2023 in “Bioactive Materials” The new hair loss treatment combining nitric oxide and minoxidil in a special carrier is effective for hair regrowth.
16 citations,
March 2008 in “International journal of pharmaceutics” Different factors like pH, gel type, and chemical enhancers affect how well hydrocortisone gets into hair follicles, and less hydrated skin doesn't work well with the test method.
32 citations,
September 2018 in “Journal of pharmaceutical sciences” The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.
33 citations,
July 2021 in “Clinical, Cosmetic and Investigational Dermatology” Nanocarrier technology in cosmetics improves ingredient delivery and effectiveness while reducing side effects.
September 2016 in “Springer eBooks” Fat-derived stem cells may help treat skin aging and hair loss.
3 citations,
July 2022 in “Dermatologic Therapy” Magnesium microneedle patches can safely improve under-eye wrinkles when used every other night for 12 weeks.
61 citations,
June 2010 in “European Journal of Pharmaceutics and Biopharmaceutics” Cationic polymers improved liposome stability and increased skin absorption of aciclovir and minoxidil.
202 citations,
June 2005 in “Aaps Pharmscitech” Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.
1 citations,
November 2011 in “Archives of Dermatology” A woman's hair loss was caused by her husband's testosterone gel and a diabetic man's nail disease led to bone infection, both treated successfully.
February 2024 in “Skin Research and Technology” Microneedle therapy combined with serum effectively increases hair count in people with hair loss, with no side effects.
14 citations,
May 2022 in “Asian Journal of Pharmaceutical Sciences” New hair follicle-targeting treatments show promise for hair disorders but need more research on safety and effectiveness.
263 citations,
February 2013 in “Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology” Polymeric nanoparticles show promise for treating skin diseases.
33 citations,
June 2007 in “International Journal of Pharmaceutics” The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.
1 citations,
July 2023 in “International Journal of Biological Macromolecules” The study created a new hair loss treatment paste that regrows hair faster and with fewer side effects than minoxidil alone.
11 citations,
October 2017 in “International Journal of Molecular Sciences” A new drug delivery system using oil body-bound oleosin-rhFGF-10 improves wound healing and hair growth in mice.
5 citations,
August 2014 in “Pharmaceutical Development and Technology” Propylene glycol and ethanol increase finasteride skin absorption, sodium lauryl sulfate doesn't.
October 2022 in “Journal of Kermanshah University of Medical Sciences” Different substances can affect how well the skin absorbs minoxidil, a hair loss drug. Caprylic acid helps the skin absorb it the best, followed by propylene glycol and water.
55 citations,
June 2009 in “Journal of Pharmaceutical Sciences” Minoxidil promotes hair growth by penetrating skin, with ethanol-containing formulas working best.
51 citations,
May 2010 in “Journal of Drug Targeting” Transcutol-containing vesicles improve minoxidil's skin penetration and hair growth promotion.
23 citations,
June 2014 in “Journal of Pharmaceutical Sciences” Finasteride cream helps hair growth with less side effects.
25 citations,
December 2013 in “Journal of Investigative Dermatology Symposium Proceedings” New methods like nanoparticles and microneedles show promise for better skin drug delivery, especially for hair disorders.
35 citations,
October 2005 in “European journal of pharmaceutics and biopharmaceutics” Polymers increased skin permeation and stability of steroid hormones in liposomal formulations.
March 2019 in “Nasza Dermatologia Online” A rare scalp condition with hair loss was correctly diagnosed and treated, leading to hair regrowth.
24 citations,
September 2020 in “Pharmaceutics” Lidocaine-loaded microparticles effectively relieve pain and fight bacteria in wounds.