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Different factors like pH, gel type, and chemical enhancers affect how well hydrocortisone gets into hair follicles, and less hydrated skin doesn't work well with the test method.

The new CoQ10 gel protects mouse skin better against aging from UV light than the old gel.

Most transgender patients getting laser hair removal before gender-affirming surgery are already on hormone therapy, which might affect the hair removal process.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Smaller nanoemulsions can penetrate skin and hair follicles better, which may be useful for delivering drugs and vaccines through the skin.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.

The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.

Hair follicles help substances penetrate the skin faster and more effectively.

The new oral testosterone pill normalized testosterone levels and lowered SHBG in men with low testosterone.

Hormones significantly affect women's sexual function, and more research is needed to improve treatments for sexual dysfunction with minimal side effects.

Hormonal changes and psychological issues can cause sexual dysfunction in postmenopausal women. Behavioral therapy is recommended first, with hormone replacement helping some symptoms but not libido. Testosterone can improve libido, but its effects on overall sexual function are unclear. Emotional and relationship issues should be addressed before using medication, and the benefits and risks of testosterone supplementation should be considered.

New treatments for male hypogonadism are effective and should be personalized.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

Testosterone is crucial for development, growth, and various body functions in mammals.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Liposomes and niosomes improve finasteride delivery for hair loss treatment.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

Testosterone in older women can increase bone density, muscle mass, fat mass, improve memory, and boost libido, but may cause nipple color changes.

A woman's virilization symptoms were caused by her partner's use of testosterone cream, which resolved after they separated.

Testosterone pellets might work for transgender men's hormone therapy, but more research is needed.

Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.

Transfollicular drug delivery is promising but needs more research to improve and understand it better.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

Niosomes improve minoxidil skin penetration for hair loss treatment.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Ethanol pretreatment affects drug penetration through skin and hair follicles.

Invasomes effectively deliver drugs through the skin and have potential for improved treatments.