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Testosterone is crucial for development, growth, and various body functions in mammals.

New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.

Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Testosterone and its metabolites have varied effects on different body systems, especially during puberty.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Young women with nonclassic congenital adrenal hyperplasia may experience worse sexual function and mild depression compared to healthy women.

Androgen treatment with dihydrotestosterone may help maintain height in patients with 5-α-reductase type 2 deficiency, especially before puberty.

A combination of nanomilled oral testosterone and dutasteride normalized testosterone levels in men with low testosterone and is safe for short-term use.

The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.

Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.

Testosterone is key for male sexual function, and treating hormone imbalances can improve sexual issues.

Muscles can make their own androgens, which may help muscle growth.

The document concludes that respectful, gender-affirming healthcare improves mental health and encourages continued medical care for transgender and non-binary individuals.

More research is needed to understand how testosterone is maintained in adult males.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.

The new oral testosterone pill normalized testosterone levels and lowered SHBG in men with low testosterone.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

5α-Reductase inhibitors may increase depression risk but not dementia or suicide.

Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.

The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.