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Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

Researchers created a model to understand heart aging, highlighting key genes and pathways, and suggesting miR-208a as a potential heart attack biomarker.

A gene network led by RSL4 is crucial for early root hair growth in response to cold in Arabidopsis thaliana.

Combining genetic and physical trait analysis improves diagnosis accuracy for monogenic diabetes.

New insights into cell communication in psoriasis suggest innovative drug treatments.

The gene Ascl4 is not necessary for the development of hair, teeth, or mammary glands.

Excess androgens may cause PCOS, not just be a symptom.

The study provides insights into hair growth mechanisms in yaks.

Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.

Hair follicles can be kept in RNAlater® at cool or room temperature for a week without harming RNA quality.

Effective PCOS treatments require targeting specific signaling pathways.

Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.

TNC+ fibroblasts play a key role in skin inflammation by interacting with T cells.

Certain long non-coding RNAs are important for controlling hair growth cycles in sheep.

The mesenchyme can start hair growth, but the exact signal that causes this is still unknown.

The article concludes that understanding the molecular processes in hair follicle development can improve the quality of fibers like Angora and cashmere.

The study aims to create a model to improve personalized and preventive health care.

Blocking IL-17 can reduce skin inflammation in a mouse model of pityriasis rubra pilaris.

Seasonal changes affect gene activity linked to hair growth in Angora goats.

Safflower extract helps protect hair follicle cells from damage caused by chemotherapy.

A specific genetic deletion in goats affects cashmere yield and thickness.

Mouse touch-sensitive nerve cells adjust their connections based on competition with other similar cells.

Melatonin affects certain genes and pathways involved in cashmere goat hair growth.

The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.

Melatonin can increase cashmere yield by altering gene expression and restarting the growth cycle early.

The SbbHLH85 protein helps sweet sorghum grow more root hairs but makes the plant more sensitive to salt.

Plant roots respond to fungus smells by possibly using certain proteins and a plant hormone to change root growth, but more research is needed.

Tiny particles from skin cells can help activate hair growth.

Platelet-rich Plasma Gel may help treat en coup de sabre scleroderma, improving symptoms and skin quality with minimal side effects.

Suppressing very long chain fatty acids is linked to skin cancer.