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The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

Advanced human skin models improve drug development and could replace animal testing.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Tiny needles with valproic acid can effectively regrow hair.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.

Msx2 and Foxn1 are both crucial for hair growth and health.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Wnt signaling is crucial for skin wound healing and reducing scars.

Inactive hair follicle stem cells help prevent skin cancer.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Lamins are vital for cell survival, organ development, and preventing premature aging.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.

PRP treatment may stimulate hair growth by promoting blood vessel formation, increasing growth factors, and preventing cell death.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

RANK-RANKL signaling is essential for hair growth and skin health.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

Testosterone may slow down wound healing and increase inflammation.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.