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George Ernest Rogers was a notable scientist who made important discoveries about hair and wool proteins.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

PGD2 stops hair growth and is higher in bald men with AGA.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Wnt ligands are crucial for hair growth and repair.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Treatments for melanin disorders exist, but more effective options needed.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.