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Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

Growing human skin cells in a 3D environment can stimulate new hair growth.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Lactate production is important for activating hair growth stem cells.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Ruxolitinib effectively regrows hair in most patients with severe hair loss.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Researchers found 19 genes important for root hair growth in a plant called Arabidopsis.

Zinc is effective for treating various skin conditions, including warts and acne.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Understanding different types of skin cells, especially fibroblasts, can lead to better treatments for wound healing and less scarring.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.