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High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Stem cell niches support, regulate, and coordinate stem cell functions.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Stem cell self-renewal is complex and needs more research for full understanding.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Different types of stem cells and their environments are key to skin repair and maintenance.

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Exosomes from dermal papilla cells can help grow hair and might treat hair loss.

Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.