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The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

Triptolide effectively and safely reduces actinic keratosis lesions in mice.

A boy with Oculodentodigital syndrome had a unique GJA1 gene mutation causing his symptoms.

The BMP/Smads pathway and Id2 gene control hair follicle stem cells, affecting their rest and growth phases.

Scientists created a tiny, 3D model of a hair follicle that grows and acts like a real one.

Swedish men with the E213 A-allele of the androgen receptor have a lower risk of prostate cancer.

New treatments for hair growth and psoriasis may be possible, and gene differences could affect baldness and the severity of skin conditions.

R-spondin2 may help treat hair loss, gene differences could explain baldness, a peptide's regulation is linked to psoriasis, B-defensin gene copies may affect a skin condition's risk and severity, and potential markers and targets for alopecia areata were identified.

Blocking Oncostatin M's role in the JAK-STAT pathway can stimulate hair growth in mice.

Blocking Prostaglandin D₂ (PGD₂) could help treat hair loss.

Gypenosides from Gynostemma pentaphyllum were found to have anti-aging effects, increasing skin collagen and reducing wrinkles.

Double-stranded RNA activates a pathway that causes a skin protein to be expressed in the wrong place.

The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

People with androgenetic alopecia may have a higher risk of heart problems compared to those with alopecia areata or healthy individuals.

People with psoriasis have more health problems, including autoimmune diseases, than those without it.

Psoriasis patients have more comorbidities, including autoimmune diseases and other health issues, than those without psoriasis.

Psoriasis is linked to a higher risk of autoimmune diseases and other health conditions.

Low-Level Laser Therapy can stimulate healing and cell function, potentially leading to wider medical use.

Adult hair follicle cells can create new hair follicles from corneal cells with the right support.

Parthenolide promotes hair growth in mice and may influence pathways related to male pattern baldness.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Fluridil safely promotes hair growth in men with androgenetic alopecia.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.