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Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.

Researchers created a model to understand heart aging, highlighting the role of microRNAs and identifying key genes and pathways involved.

A new MBTPS2 gene variant disrupts fat metabolism and collagen production, causing Osteogenesis imperfecta.

The document concludes that pig iPSCs show promise for transplant therapies and the field is advancing in controlling cell behavior for biology and medicine.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Lamins are vital for cell survival, organ development, and preventing premature aging.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

Zinc can both inhibit and stimulate mouse hair growth, and might help recover hair after chemotherapy.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

Key genes are crucial for Drosophila wing development and could be insecticide targets.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.