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Gentamicin penetrates pig skin better through open hair follicles than blocked ones.

Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.

Lipid nanoparticles improve drug delivery through the skin, offering stability, controlled release, and better compatibility with skin.

Minoxidil in distearyldimethylammonium chloride vesicles significantly promotes hair growth, while minoxidil in microparticles or poloxamer solutions doesn't.

Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.

Plant-derived extracellular vesicles show promise for treating diseases like cancer and inflammation.

Removing the outer skin layer increases drug absorption and offers non-invasive treatment options, with some methods allowing for quick skin recovery.

Innovative methods are reducing animal testing and improving biomedical research.

Nanoparticle-based herbal remedies could be promising for treating hair loss with fewer side effects and lower cost, but more research is needed.

Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.

Nanotechnology shows promise for better drug delivery and cancer treatment.

Keratin proteins are crucial for hair structure and strength.

Infrared light can trigger drug release from gold nanoparticle carriers in hair follicles.

Proretinal nanoparticles improve skin absorption and reduce irritation of topical retinoids.

Melatonin-loaded microemulsion could be a promising treatment for hair loss.

New skin disease treatments using TDDS are improving but face challenges like side effects and high costs.

Minoxidil-loaded nanoparticles effectively promote hair regrowth and are safe for use.

Minoxidil's absorption is too variable for it to be a reliable reference drug.

Vitamin D is important for bones, hair, blood pressure, and breast development.

Essential oils from Curcuma species, like turmeric, have compounds that can fight inflammation, cancer, and bacteria, and can also stimulate hair regrowth in bald males.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

New nanocarriers improve drug delivery for disease treatment.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Keratin proteins are essential for keeping the cells in the human colon healthy and stable.

Nanoparticles added to natural materials like cellulose and collagen can improve cell growth and wound healing, but more testing is needed to ensure they're safe and effective.

Minoxidil and finasteride are the best for non-scarring hair loss; more research is needed for scarring hair loss treatments.

Diamond nanoparticles can penetrate skin and reach hair follicles, useful for imaging applications.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Nanoemulgel is a better way to deliver drugs through the skin for various conditions.

Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.