research Formation of the Iε-(γ-Glutamyl)Lysine Crosslink in Hair Proteins: Investigation of Transamidases in Hair Follicles
Transamidases help form strong crosslinks in hair proteins, crucial for hair strength.
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research Ingestion of Minoxidil Associated with Elevated Transaminases in the Absence of Ischemic Hepatitis
Minoxidil ingestion can raise liver enzyme levels.
research A Phase IIA Randomized, Placebo-Controlled Clinical Trial to Study the Efficacy and Safety of the Selective Androgen Receptor Modulator (SARM), MK-0773 in Female Participants with Sarcopenia
MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.
research Prevalence of Hepatic Steatosis in Women with Polycystic Ovary Syndrome
Women with PCOS are more likely to have fatty liver disease, especially if they have metabolic problems.
research Granulomatous Skin Involvement in a Patient with an Unusual NOD2 Mutation
A rare genetic mutation caused unusual skin symptoms in a man with Blau syndrome.
research Acitretin
Acitretin treats severe skin conditions but requires careful monitoring due to serious side effects.
research Safety of Oral Bicalutamide in Female Pattern Hair Loss: A Retrospective Review of 316 Patients
Oral bicalutamide is safe and effective for female hair loss.
research Experience with Oral Tofacitinib in Severe Alopecia Areata with Different Clinical Responses
Oral tofacitinib helped regrow hair in over half of the patients with severe alopecia, but relapses and side effects were common.
research Bicalutamide: A Potential New Oral Antiandrogenic Drug for Female Pattern Hair Loss
Bicalutamide may be a promising alternative treatment for female pattern hair loss.
research Metreleptin Treatment in a Boy with Congenital Generalized Lipodystrophy Due to Homozygous c.465_468delGACT (p.T156Rfs*8) Mutation in the BSCL2 Gene: Results From the First Year
Metreleptin treatment significantly improved metabolic health in a boy with congenital generalized lipodystrophy.
research Response of Alopecia Areata of the Beard to Oral Tofacitinib
Oral tofacitinib is a promising treatment for beard hair loss in alopecia areata.
research Autoimmune Liver Disease in Children
Autoimmune hepatitis in children often affects girls and can be treated successfully with medication.
research Comparative Analysis of Safety Data of Four Treatment Regimens in Early Rheumatoid Arthritis Patients
Methotrexate plus prednisolone had the fewest serious side effects.
research Effects of Abuse of Anabolic Androgenic Steroids on Iraqi Athletes
Abuse of anabolic steroids in Iraqi athletes leads to negative effects on hormones, liver and kidney function, blood sugar, and cholesterol levels.
research A Study on the Clinical Profile and Pharmacogenetics of Methotrexate Treatment in Patients with Rheumatoid Arthritis
The 1298CC genotype in RA patients leads to higher methotrexate toxicity, while the 1298AA genotype results in better treatment response.
research Oral Retinoids: Present Status
Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.
research Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity
Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
research Telogen Effluvium Due to Recombinant Interferon Alpha-2b
Half of the patients treated with a specific drug for skin cancer experienced hair loss not related to the drug's dosage.
research Evaluation of Clinical Adverse Effects and Laboratory Changes in Patients with Acne Vulgaris Treated with Oral Isotretinoin
Isotretinoin is safe and effective for acne, with common side effects like dry lips; serious side effects are rare.
research Efficacy of Oral Retinoids in Treatment-Resistant Lichen Planopilaris
Oral retinoids may help some patients with hard-to-treat lichen planopilaris, but more research is needed.
research Effective Amelioration of Hepatic Inflammation and Insulin Response in High-Fat Diet-Fed Rats via Regulating AKT/mTOR Signaling: Role of Lepidium Sativum Seed Extracts
Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.
research Alopecia Universalis as a Side Effect of Pegylated Interferon α-Ribavirin Combination Therapy for Hepatitis C: A Rare Case Report
A man lost all his hair as a rare side effect after hepatitis C treatment.
research Chronic Crusted Scalp Lesion of an Elderly Male
An elderly man's non-healing scalp lesion was successfully treated with a strong topical steroid.
research Hepatotoxicity Secondary to a Weight Loss Drug, Orlistat: Consideration as a Differential Diagnosis
The weight loss drug Orlistat can cause liver damage and should be used with caution, especially in those with liver or kidney issues.
research Systemic Diseases Associated with Primary Biliary Cirrhosis: A Report of 10 Cases
Early detection and treatment of primary biliary cirrhosis and related autoimmune diseases improve outcomes.
research Efficacy of Topical Nanoemulsion (NB-002) for the Treatment of Distal Subungual Onychomycosis: A Randomized, Double-Blind, Vehicle-Controlled Trial
NB-002 is a promising new topical treatment for fungal nail infections, showing better results than a non-medicated option.
research Evaluation of the Activity of Laser Light Doses Compared to an Inactive Control Dose on Ex Vivo Hair Growth
Low-level laser therapy increased hair growth compared to no treatment.
research A Randomized, Placebo- and Active-Controlled, Parallel-Group, Multicenter, Investigator-Blinded Study of Four Treatment Regimens of Posaconazole in Adults with Toenail Onychomycosis
Posaconazole is a promising new treatment for toenail fungus.
research Hair Care Practices in Different Populations: What Makes a Difference?
Social or cultural norms, not hair type, more likely influence how often people wash their hair.
research Adverse Reactions to Anthelminthic Drugs
Some people have severe allergic reactions to anthelminthic drugs, but these are often due to the parasites, not the drugs.