research Formation of the Iε-(γ-Glutamyl)Lysine Crosslink in Hair Proteins: Investigation of Transamidases in Hair Follicles
Transamidases help form strong crosslinks in hair proteins, crucial for hair strength.
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research A Phase IIA Randomized, Placebo-Controlled Clinical Trial to Study the Efficacy and Safety of the Selective Androgen Receptor Modulator (SARM), MK-0773 in Female Participants with Sarcopenia
MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.
research Acitretin
Acitretin treats severe skin conditions but requires careful monitoring due to serious side effects.
research Granulomatous Skin Involvement in a Patient with an Unusual NOD2 Mutation
A rare genetic mutation caused unusual skin symptoms in a man with Blau syndrome.
research Prevalence of Hepatic Steatosis in Women with Polycystic Ovary Syndrome
Women with PCOS are more likely to have fatty liver disease, especially if they have metabolic problems.
research Metreleptin Treatment in a Boy with Congenital Generalized Lipodystrophy Due to Homozygous c.465_468delGACT (p.T156Rfs*8) Mutation in the BSCL2 Gene: Results From the First Year
Metreleptin treatment significantly improved metabolic health in a boy with congenital generalized lipodystrophy.
research Ingestion of Minoxidil Associated with Elevated Transaminases in the Absence of Ischemic Hepatitis
Minoxidil ingestion can raise liver enzyme levels.
research Bicalutamide: A Potential New Oral Antiandrogenic Drug for Female Pattern Hair Loss
Bicalutamide may be a promising alternative treatment for female pattern hair loss.
research Experience with Oral Tofacitinib in Severe Alopecia Areata with Different Clinical Responses
Oral tofacitinib helped regrow hair in over half of the patients with severe alopecia, but relapses and side effects were common.
research Safety of Oral Bicalutamide in Female Pattern Hair Loss: A Retrospective Review of 316 Patients
Oral bicalutamide is safe and effective for female hair loss.
research Response of Alopecia Areata of the Beard to Oral Tofacitinib
Oral tofacitinib is a promising treatment for beard hair loss in alopecia areata.
research Serum Biotinidase Activity in Children Treated With Valproic Acid and Carbamazepine
Valproic acid does not change biotinidase enzyme activity in children's blood.
research Autoimmune Liver Disease in Children
Autoimmune hepatitis in children often affects girls and can be treated successfully with medication.
research Faculty Opinions Recommendation of Safety of Oral Bicalutamide in Female Pattern Hair Loss: A Retrospective Review of 316 Patients
research Effects of Abuse of Anabolic Androgenic Steroids on Iraqi Athletes
Abuse of anabolic steroids in Iraqi athletes leads to negative effects on hormones, liver and kidney function, blood sugar, and cholesterol levels.
research Adult Kawasaki's Disease with Myocarditis, Splenomegaly, and Highly Elevated Serum Ferritin Levels
Kawasaki's disease can occur in adults and should be considered with specific symptoms and high ferritin levels.
research A Study on the Clinical Profile and Pharmacogenetics of Methotrexate Treatment in Patients with Rheumatoid Arthritis
The 1298CC genotype in RA patients leads to higher methotrexate toxicity, while the 1298AA genotype results in better treatment response.
research Serum and Liver Tissue Biotinidase Enzyme Activity in Rats Administered Valproic Acid
Valproic acid may cause hair loss by reducing biotinidase enzyme activity in rats.
research Comparative Analysis of Safety Data of Four Treatment Regimens in Early Rheumatoid Arthritis Patients
Methotrexate plus prednisolone had the fewest serious side effects.
research Oral Retinoids: Present Status
Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.
research Systemic Diseases Associated with Primary Biliary Cirrhosis: A Report of 10 Cases
Early detection and treatment of primary biliary cirrhosis and related autoimmune diseases improve outcomes.
research Hepatic Steatosis and Acute Liver Injury in Chronic Arsenic Exposure
Chronic arsenic exposure can cause liver damage and other health issues.
research Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity
Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
research Pembrolizumab-Induced Autoimmune Hepatitis
Pembrolizumab can cause serious liver issues, requiring close monitoring and early treatment.
research Sodium Valproate for Painful Peripheral Neuropathy in Diabetic Patients
Sodium valproate is not recommended as a first-line treatment for neuropathy but may be used in resistant cases.
research Adverse Reactions to Anthelminthic Drugs
Some people have severe allergic reactions to anthelminthic drugs, but these are often due to the parasites, not the drugs.
research Chronic Crusted Scalp Lesion of an Elderly Male
An elderly man's non-healing scalp lesion was successfully treated with a strong topical steroid.
research Effective Amelioration of Hepatic Inflammation and Insulin Response in High-Fat Diet-Fed Rats via Regulating AKT/mTOR Signaling: Role of Lepidium Sativum Seed Extracts
Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.
research Evaluation of the Activity of Laser Light Doses Compared to an Inactive Control Dose on Ex Vivo Hair Growth
Low-level laser therapy increased hair growth compared to no treatment.
research Hair Care Practices in Different Populations: What Makes a Difference?
Social or cultural norms, not hair type, more likely influence how often people wash their hair.