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New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

New compounds with carborane showed anti-androgen effects similar to flutamide.

Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.

Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

The Hr protein binds to DNA, interacts with p53, and affects cell cycle genes.

Broussonetia papyrifera extract helps hair growth by regulating specific proteins.

MAD2B slows down the growth of skin cells that are important for hair development by interacting with TCF4.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.

ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Sex steroids affect the MafB gene differently in male and female hamsters.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Reduced AR gene methylation may cause early pubic hair growth in girls.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.

Vitamin D receptor can control the hairless gene linked to hair loss even without vitamin D.

A new gene mutation may allow some piebaldism patients to regain skin color in white patches.

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.