Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that the EDAR 1540T/C genetic variant is significantly associated with hair thickness variation in Japanese populations, enhancing previously observed associations in Southeast Asian groups.

This study found that miR-133a-3p and miR-145-5p influenced goat hair follicle stem cell differentiation by inhibiting NANOG expression and promoting SOX9 expression.

In this study, 17β-estradiol increased VEGF production in differentiated THP-1 cells, while dihydrotestosterone counteracted this effect by modulating adenylate cyclase activity.

This study found that prostaglandin D2 reduced proliferation in bulge resident K15+ stem cells but not in other K15+ progenitor cells, suggesting differential impacts on hair follicle stem cell niches.

This exploratory study found that cannabidiol (CBD) at higher concentrations may inhibit hair growth by promoting the onset of catagen in human hair follicles, while lower concentrations showed potential anti-inflammatory effects without promoting catagen.

This study highlights that human hair follicle dermal papilla cells and glypicans play crucial roles in regulating hair follicle stem cell differentiation.

This study assessed three lactic acid bacteria-fermented proteins and found that F-WPI and F-SPI could normalize osteoclastogenesis markers in vitro, while F-SPI enhanced osteoblastogenesis markers, suggesting potential as dietary supplements for osteoporosis prevention, though further research into mechanisms is needed.

This study found differential expression of growth factors and cytokines in umbilical cord blood-derived platelet-rich plasma, with the highest concentrations observed in the B blood type, but also noted weak correlations with ABO blood groups, suggesting other influencing factors.

This review covers recent developments in materials for in vitro and in vivo stem cell manipulation, highlighting innovative substrate properties but does not report new experimental results.

This study found that transient activation of c-Myc in transgenic mice stimulates keratinocyte proliferation and sebocyte differentiation, affecting normal epidermal and hair follicle development.

This review discusses the role of miRNA/mRNA regulatory networks in skin development, epidermal homeostasis, and tissue remodeling, and suggests potential for miRNA-based therapies in treating skin conditions, but reports no new clinical results.

In this mouse study, researchers found that dermal Wnt signaling/β-catenin activity is essential for fibroblast proliferation and initiating hair follicle formation by interacting with epidermal Wnt ligands.

This review discusses how Western diet may contribute to acne vulgaris through insulin signaling and metabolomic changes, promoting a dietary approach for management, but reports no new experimental results.

This review highlights similarities in the development of thymus and skin epidermis, reporting no new results; the authors emphasize shared molecular mechanisms despite different embryonic origins.

This study reports new cellular features and complex interaction systems in fiber differentiation, indicating more intricate cellular organization than previously recognized, including features like mast cells and primary cilia.

This study suggests that the protease HAT-L4 plays a significant role in maintaining epidermal barrier function to prevent body fluid loss, as its absence in mice led to increased fluid loss and higher mortality.

This study observed that inducible deletion of the Ugcg gene in mouse epidermis led to a significant reduction in GlcCers and epidermal POS-Cers, causing impaired skin barrier function and delayed wound healing.

This study reports on a patient whose symptoms, including trichoepitheliomas and clinical alopecia, may suggest a new syndrome possibly linked to myasthenia gravis.

This study explored how modifying the 8-substituent of 8-bromobenzoquinolinone affects its selectivity in inhibiting both 5 alpha-reductase isozymes in the scalp.

In this case report, researchers documented a rare instance of trans-epidermal elimination of insulin formulation in a 45-year-old woman with diabetes, suggesting that insulin or its excipients may have caused a granulomatous reaction leading to skin lesions at injection sites and impaired diabetes control.

This study found that the genes FCER1A and RGS1 are promising biomarkers for diagnosing systemic lupus erythematosus, with FCER1A downregulated and RGS1 upregulated in patients.

In this animal study, researchers found that the simultaneous deletion of ERBB2 and ERBB3 in mice results in impaired skin differentiation, inflammation, and sebaceous gland alteration, leading to skin lesions, while highlighting potential side effects in cancer therapies targeting these receptors.

This study reports that dynamic interactions between stem cells and their niche, influenced by macro-environmental factors, regulate regenerative behavior in integument pattern formation.

This review summarizes fundamental concepts and recent advancements in hair follicle biology, including insights from mouse models into broader molecular and cellular processes relevant to regeneration and development.

This article reviews the complex signaling pathways between epithelial and mesenchymal cells crucial for hair follicle morphogenesis, highlighting the Wnt pathway's role as a master regulator without reporting new experimental findings.

This study found that overexpression of activin in transgenic mice led to enhanced granulation tissue formation after skin injury due to changes in keratinocyte proliferation and differentiation.

This review explores the role of TGF-β superfamily pathways in stem cell environments and their implications for tissue regeneration and cancer development, reporting no new experimental results.