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This review discusses recent findings on fibrotic lipodystrophy, highlighting the critical roles of lipid-filled cells in tissue function and their loss during fibrogenesis, with implications for fibrosis in tissues like skin, lung, and liver.

This review discusses the molecular mechanisms driving hair follicle degeneration in skin aging and emphasizes the role of the tissue microenvironment on stem cell function, but reports no new research findings.

This study found that UVB irradiation alters skin stem cell niches leading to signs of photoaging, which may be reversed by adipose-derived stem cells through BMP4 pathway modulation and niche remodeling.

This study found that mesenchymal stem cells showed potential to differentiate into hair follicle stem cells when induced by the supernatant of cultured hair follicles in vitro.

In this study, K19-lacZ transgenic mice exhibited epithelial-specific reporter gene expression in tissues such as the pancreas and stomach, suggesting the K19 promoter is a valuable tool for studying epithelial cell biology.

The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.

In this study of clinical-grade ADMSCs, researchers found that cells expanded in PowerStem MSC1 media exhibited increased negative marker expression, chromosomal abnormalities, and signs of senescence compared to those cultured in StemMACS MSC Expansion Media, suggesting that the latter is more suitable for therapeutic applications.

This study suggests that StemMACS MSC Expansion Media is more suitable than PowerStem MSC1 media for expanding therapeutic adipose-derived mesenchymal stem cells, with less expression of negative markers and better chromosomal stability.

This study found that deleting the transcription factor Twist1 in keratinocytes significantly reduced UVB-induced skin carcinogenesis in mice, suggesting a potential target for preventing cutaneous squamous cell carcinoma.

This review discusses the dynamic changes in chromatin organization and nuclear morphology during cellular processes like differentiation and disease, highlighting recent advances in understanding these epigenetic mechanisms without presenting new experimental findings.

This study found that Tcf3 and Lef1 differently regulate cell differentiation in multipotent skin stem cells, with Tcf3 promoting follicle-like features and Lef1, when modified, promoting sebocyte differentiation.

This study found that overexpressing the BMP inhibitor Noggin in transgenic mice led to a significant loss of nontylotrich hair follicles, suggesting a critical role for BMP signaling in hair follicle morphogenesis and cycling.

This study found that testosterone and dihydrotestosterone can induce growth factors from dermal fibroblasts, promoting keratinocyte proliferation and differentiation, which may contribute to sex hormone-related acne development.

This study found that COL17 plays a key role in regulating epidermal keratinocyte differentiation and proliferation, influencing the expression of differentiation markers and cellular growth in specific conditions.

This study found that forming spheroids using silicone micro-wells improved the viability and neural differentiation potential of human adipose-derived stem cells after thawing.

This study concluded that hair-derived stem cells from older donors may offer a promising alternative for autologous corneal endothelial replacement, potentially benefitting patients of various age groups.

This study found that cathepsin L deficiency in mice led to significant abnormalities in hair follicle development and cycling, including disrupted hair shaft outgrowth and premature hair growth phase entry.

In this study, researchers found that TCDD exposure accelerated differentiation and altered gene expression in human epidermal cells, indicating the epidermal barrier as a target of TCDD-activated AHR.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

This study found that human hair follicle-derived mesenchymal stem cells can differentiate into myogenic, osteogenic, adipogenic, and chondrogenic lineages, although this potential decreases over time and varies by lineage.

This study demonstrated that intact adult human dermal papillae can induce hair growth when implanted into mouse hair follicles, highlighting their potential for advancing hair follicle biology and therapeutic approaches.

This study found that thyroxine modulates peripheral molecular clock gene expression in human hair follicles, which may have implications for treating clock-related diseases in patients with thyroid dysfunction.

The study suggests that a 3D culture system using the RAD16-I peptide scaffold can help restore the original phenotype of hair follicle dermal papilla cells and support their osteogenic and adipogenic differentiation.

This study found various ABC transporters are transcribed in human hair follicles, suggesting their possible role in HF biology and potential for new therapeutic interventions.

This study found that upregulation of NFIC may enhance proliferation and osteogenic/cementogenic differentiation in rat dental follicle cells.

This study found that dermal EZH2 plays a crucial role in controlling fibroblast differentiation by regulating Wnt/β-catenin and retinoic acid signaling during skin development.

This study found that ingenol mebutate treatment led to gene expression changes in actinic keratoses, with complete lesion clearance in 40% of patients and identified genetic markers potentially predicting treatment response.

This article reviews current research on epidermal stem cells and differentiation, presenting models of basal layer composition, but reports no new experimental findings.

The study found that dermal EZH2 plays a crucial role in coordinating dermal fibroblast differentiation and epidermal development by modulating Wnt/β-catenin and retinoic acid signaling.

This study found that the Polycomb Repressive Complex 2, particularly its component Ezh2, is crucial in regulating dermal fibroblast differentiation and epidermal keratinocyte proliferation during murine skin development.