research The Fatty Acids and the Skin: A Focus on the N-6 Family of Unsaturated Fatty Acids
Linoleic acid is essential for healthy skin, and while deficiency is rare in Western societies, it can cause dry, scaly skin and hair loss.
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research Female Pattern Hair Loss with Acromegaly
Hair loss improved after removing pituitary tumor.
research Topical Tretinoin for Hair Growth Promotion
Tretinoin may help hair growth and works better when combined with minoxidil.
research The RAIG Family Member, GPRC5D, Is Associated With Hard-Keratinized Structures
GPRC5D is linked to the formation of hair, nails, and certain tongue areas.
research Polymer Conjugated Retinoids for Controlled Transdermal Delivery
A new method allows for controlled, long-lasting delivery of retinoic acid through the skin with fewer side effects.
research Retinoid-Mediated Stimulation of Steroid Sulfatase Activity in Myeloid Leukemic Cell Lines Requires RARα and RXR and Involves the Phosphoinositide 3-Kinase and ERK-MAP Kinase Pathways
Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
research Endogenous Skin Fluorescence Is a Good Marker for Objective Evaluation of Comedolysis
Fluorescence can effectively measure acne treatment progress.
research Effect of Retinoids on Follicular Cells
Retinoids can change the hair growth cycle by extending the growth phase and shortening the rest phase.
research Deriving Keratinocyte Progenitor Cells and Keratinocytes from Human-Induced Pluripotent Stem Cells
Scientists developed a way to create skin and hair cells from human stem cells, which could help treat burns and restore hair.
research Retinol Dehydrogenase 12 (RDH12): Role in Vision, Retinal Disease, and Future Perspectives
The enzyme RDH12 plays a role in vision and retinal disease, with mutations leading to early onset visual loss and blindness, but the exact disease mechanism is unclear and there are no treatments yet.
research From Molecular Biology to Therapeutics
The document discusses various skin disorders and new therapeutic approaches.
research The Effect of Dietary Change on In Vitro Erythrocyte Hemolysis, Skin Lesions, and Alopecia in Common Marmosets (Callithrix Jacchus)
A diet high in vitamin E improved blood health, skin, and fur in common marmosets.
research Aberrant Wnt Signaling Induces Comedo-Like Changes in the Murine Upper Hair Follicle
Overactive Wnt signaling in mouse skin stem cells causes acne-like cysts and shrinking oil glands, which some treatments can partially fix.
research Anti-Aging Effects of Retinoid Hydroxypinacolone Retinoate on Skin Models
Hydroxypinacolone retinoate is a potent anti-aging ingredient for skin that is more effective and less irritating than other forms of retinoids.
research Connective Tissue Sheath of Hair Follicle Is a Major Source of Dermal Type I Procollagen in Human Scalp
The hair follicle's connective tissue is a key source of a certain collagen in human scalp skin.
research Cultivation of Hair Matrix Cells from Cashmere Goat Skins and Exemplified Applications
Researchers found a way to grow cashmere goat hair cells in a lab and discovered that certain conditions improve these cells' growth and characteristics.
research Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1
Vitexin Compound 1 may help reduce skin aging caused by UVA light.
research Vitamin A Resolves Lineage Plasticity to Orchestrate Stem Cell Lineage Choices
Vitamin A helps skin stem cells decide their function, aiding in hair growth and wound repair.
research Aberrant Wnt Signaling Induces Comedo-Like Changes in the Upper Hair Follicle
Abnormal Wnt signaling in hair follicle stem cells can lead to acne-like cysts.
research Role of the ABCA4 Gene Expression in the Clearance of Toxic Vitamin A Derivatives in Human Hair Follicle Stem Cells and Keratinocytes
The ABCA4 gene protects hair follicle stem cells from toxic vitamin A byproducts.
research Regulation of Epidermal Proliferation and Hair Follicle Cycling by Synthetic Photostable Retinoid EC23
The synthetic retinoid EC23 thickens skin and promotes hair growth more effectively and with a lower dose than natural retinoids.
research Side Effects of Vitamins, Amino Acids, Nutrition, and Complementary and Alternative Medicine
Some vitamins, amino acids, and alternative medicines can cause serious side effects, including bone, muscle, and skin issues, and healthcare professionals should be aware of these risks.
research Polymer Conjugated Retinoids for Controlled Transdermal Delivery
A new method allows for controlled, long-lasting delivery of retinoic acid through the skin with less inflammation.
research In This Issue
The studies identified key factors and potential treatments for skin and hair disorders.
research Morpho-Regulation of Ectodermal Organs
Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
research Small Molecules and Small Molecule Drugs in Regenerative Medicine
Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.
research Outperforming Ourselves: Invitation for Dialogue
The critique suggests that Wilton's work unintentionally supports the very stereotypes it aims to question and calls for a broader, more inclusive approach to understanding gender.
research Dermatologic Care of the Lesbian, Gay, Bisexual, and Transgender Community of India
The transgender community in India has specific skin care needs and struggles to access dermatological services due to discrimination and financial issues.
research Epithelial-Mesenchymal Interactions Promote Hair Follicle Neogenesis and a New Stem Cell Niche in Adult Corneal Epithelium
Adult hair follicle cells can create new hair follicles from corneal cells with the right support.
research Recommendations for Endocrine Treatment of Patients with Gender Dysphoria
The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.