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    Glossary Tranexamic Acid

    medication that reduces bleeding by preventing clot breakdown

    Tranexamic Acid (TXA) is a medication that helps reduce bleeding by inhibiting the breakdown of blood clots. It is commonly used in surgeries, trauma cases, and to treat heavy menstrual bleeding. By blocking the action of plasmin, an enzyme involved in clot degradation, TXA helps stabilize clots and prevent excessive blood loss.

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    1. A pilot study for triple combination therapy with a low-fluence 1064 nm Q-switched Nd:YAG laser, hydroquinone cream and oral tranexamic acid for recalcitrant Riehl’s Melanosis Journal of dermatological treatment · 2016 · 36 citations
    2. Co-Drug Strategy for Promoting Skin Targeting and Minimizing the Transdermal Diffusion of Hydroquinone and Tranexamic Acid Current medicinal chemistry · 2013 · 21 citations
    3. Ameliorative effect of tranexamic acid on physiological skin aging and its sex difference in mice Archives of dermatological research · 2019 · 13 citations
    4. Tranexamic acid reduces inflammation, edema and burn wound conversion in a rodent model Burns · 2024 · 8 citations
    5. The Role of gp91phox and the Effect of Tranexamic Acid Administration on Hair Color in Mice International Journal of Molecular Sciences · 2019 · 2 citations
    6. 10. EVALUATION OF THE EFFICACY AND SAFETY FOR THE COMBINATION USE OF ORAL AND TOPICAL TRANEXAMIC ACID IN THE TREATMENT OF MELASMA AT HO CHI MINH CITY DERMATOLOGY HOSPITAL Tạp chí Y học Cộng đồng · 2024
    7. Clinical and Dermoscopic Evaluation of the Efficacy Melasma Treatment with Oral Tranexamic Acid 2023
    8. Efficacy and safety of microneedling and oral tranexamic acid in the treatment of facial melasma in women: An open, evaluator-blinded, randomized clinical trial Journal of the American Academy of Dermatology · 2020 · 13 citations
    9. Œdème angioneurotique sans anomalie de l’inhibiteur de la C1 estérase : efficacité de l’acide tranexamique Annales de Dermatologie et de Vénéréologie · 2006
    10. Melasma, a photoaging disorder Pigment cell & melanoma research · 2017 · 144 citations
    11. Is skin microneedling a good alternative method of various skin defects removal Dermatologic Therapy · 2018 · 23 citations
    12. Topical and Systemic Therapies in Melasma: A Systematic Review Indian Dermatology Online Journal · 2023 · 10 citations
    13. Platelet-Rich Plasma in Melasma—A Systematic Review Dermatologic Surgery · 2021 · 5 citations
    14. Lichen Planus Pigmentosus in North Africa: A Series of 17 Cases Dermatology - Open Journal · 2019 · 4 citations
    15. Efficacy and Safety of Platelet-Rich Plasma in Melasma: A Systematic Review Cureus · 2024 · 3 citations
    16. 452: HAIR-RAISING TOXICITY: STATUS EPILEPTICUS FOLLOWING HAIR RESTORATION DUE TO LAST AND TXA TOXICITY Critical Care Medicine · 2026
    17. Search Advances in Lip Skin Biology and Anti-Aging Strategies International Research Journal of Modernization in Engineering Technology and Science · 2026
    18. Position of systemic therapy in the treatment of lichen pigmentosus Our Dermatology Online · 2025
    19. Nutrological control and treatment of melasma in the COVID-19 pandemic: a concise systematic review International Journal of Nutrology · 2022
    20. A comment on a study of donor area in follicular unit hair transplantation Journal of Cutaneous and Aesthetic Surgery · 2014
    21. Unmasking Melasma: Confronting the Treatment Challenges Cosmetics · 2024 · 1 citations
    22. Vesicles: Potential nano carriers for the delivery of skin cosmetics Journal of Cosmetic and Laser Therapy · 2017 · 21 citations
    23. Advancing the Understanding and Management of Segmental Vitiligo and Co‐Existing Pigmentary Disorders International Journal of Dermatology · 2025
    24. ОСТРЫЙ ПОСТОПЕРАЦИОННЫЙ БОЛЕВОЙ СИНДРОМ У ПАЦИЕНТОВ РИНОХИРУРГИЧЕСКОГО ПРОФИЛЯ ПОСЛЕ ИСПОЛЬЗОВАНИЯ ПОПУЛЯРНЫХ МЕТОДОВ АНЕСТЕЗИИ В Г. МОСКВЕ. Голова и шея. · 2022 · 1 citations
    25. Issue Information Clinical and Experimental Dermatology · 2017
    26. Skin Pigmentation Types, Causes and Treatment—A Review Molecules · 2023 · 138 citations
    27. A Comprehensive Review on Skin Pigmentation-Types, Causes, and Treatment Preprints.org · 2023 · 32 citations
    28. Spotlight in Plastic Surgery: October 2022 Plastic and Reconstructive Surgery · 2022
    29. Azelaic Acid: Mechanisms of Action and Clinical Applications Clinical Cosmetic and Investigational Dermatology · 2024 · 34 citations
    30. Modulatory role of vitamins A, B3, C, D, and E on skin health, immunity, microbiome, and diseases Pharmacological Reports · 2023 · 47 citations