research Molecular Signaling in Feather Morphogenesis
Feather growth and regeneration involve complex patterns, stem cells, and evolutionary insights.
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research MiR-218-5p Regulates Skin and Hair Follicle Development Through Wnt/β-Catenin Signaling Pathway by Targeting SFRP2
miR-218-5p helps skin and hair growth by targeting SFRP2 and activating a specific signaling pathway.
research Glucocorticoid Receptor Mutants Demonstrate Increased Motility Inside the Nucleus of Living Cells: Time of Fluorescence Recovery After Photobleaching Is an Integrated Measure of Receptor Function
Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.
research Activation of Beta-Catenin Signaling in CD133-Positive Dermal Papilla Cells Drives Postnatal Hair Growth
Activating β-catenin in certain skin cells speeds up hair growth in mice.
research Hedgehog And Gli Signaling In Embryonic Mammary Gland Development
Hedgehog signaling is crucial for mammary gland development over hair follicles.
research Dihydrotestosterone-Induced Hair Regrowth Inhibition by Activating Androgen Receptor in C57BL6 Mice Simulates Androgenetic Alopecia
DHT stops hair regrowth in mice, similar to human hair loss.
research Androgenetic Alopecia: Combing the Hair Follicle Signaling Pathways for New Therapeutic Targets and More Effective Treatment Options
New treatments for hair loss may target specific pathways and generate new hair follicles.
research Recent Discoveries and Developments of Androgen Receptor-Based Therapy for Prostate Cancer
New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.
research Basal Cell Carcinoma, Hedgehog Signaling, and Targeted Therapeutics: The Long and Winding Road
New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.
research Effective Amelioration of Hepatic Inflammation and Insulin Response in High-Fat Diet-Fed Rats via Regulating AKT/mTOR Signaling: Role of Lepidium Sativum Seed Extracts
Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.
research Allopregnanolone Is Required for Prepulse Inhibition Deficits Induced by D1 Dopamine Receptor Activation
Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.
research Smoothened Receptor Inhibitor Vismodegib for the Treatment of Basal Cell Carcinoma: A Retrospective Analysis of Efficacy and Side Effects
Vismodegib is effective for basal cell carcinoma but has severe side effects.
research Role of the Wnt Signaling Pathway in Keratoacanthoma
The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.
research FLCN Regulates Transferrin Receptor 1 Transport and Iron Homeostasis
FLCN helps control iron levels in cells.
research A Study of the Androgen Receptor Gene Polymorphism and the Level of Expression of the Androgen Receptor in Androgenetic Alopecia Among Egyptians
The study suggests that a specific gene variation and higher gene activity are linked to increased baldness in Egyptian men.
research Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice
Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
research The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed
The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
research Wnt Signaling, Lgr5, and Stem Cells in the Intestine and Skin
Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.
research WNT Signaling in the Control of Hair Growth and Structure
The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.
research Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development
Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
research The Disintegrin/Metalloproteinase Adam10 Is Essential for Epidermal Integrity and Notch-Mediated Signaling
Adam10 enzyme is crucial for healthy skin and proper Notch signaling.
research Therapeutic Anti-Inflammatory Potential of Formyl-Peptide Receptor Agonists
Formyl-peptide receptor agonists could be new anti-inflammatory drugs.
research Lichen Planopilaris Treated With a Peroxisome Proliferator-Activated Receptor Gamma Agonist
A specific drug can help treat Lichen Planopilaris, a condition causing permanent hair loss.
research Wnt Signaling Regulates Symmetry of Division of Neural Stem Cells in the Adult Brain and in Response to Injury
Wnt signaling helps control how brain stem cells divide and is important for brain repair after injury.
research Androgenetic Alopecia: Identification Of Four Genetic Risk Loci And Evidence For The Contribution Of WNT Signaling To Its Etiology
Four genetic risk spots found for hair loss, with WNT signaling involved and a link to curly hair.
research Targeting the Pre-Receptor Metabolism of Cortisol as a Novel Therapy in Obesity and Diabetes
Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.
research Wnt Signaling: The Good and the Bad
Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.
research Hair Growth-Promoting Effect of Aconiti Ciliare Tuber Extract Mediated by the Activation of Wnt/β-Catenin Signaling
Aconiti Ciliare Tuber extract may help hair grow by activating a specific cell signaling pathway.
research Hes1 Regulates Anagen Initiation and Hair Follicle Regeneration Through Modulation of Hedgehog Signaling
Hes1 protein is important for hair growth and regeneration, and could be a potential treatment for hair loss.
research Telomere Dysfunction Impairs Epidermal Stem Cell Specification and Differentiation by Disrupting BMP/pSmad/P63 Signaling
Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.