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Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.

Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Silicon can improve skin and hair health, but more research is needed.

Vitamin C helps adipose-derived stem cells grow and may support hair growth.

Taking L-cystine and vitamin B6 can prevent hair loss caused by smoke in mice.

Minoxidil and ATRA together boost hair growth more effectively than minoxidil alone.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

Isotretinoin effectively reduces acne but causes dry skin, higher skin pH, more redness, and hair loss.

The document concludes that there are various treatments for different types of alopecia, but more research is needed for evidence-based treatments.

Potassium channel openers like minoxidil help hair grow by acting on hair follicles.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Finasteride and minoxidil together promote hair growth better than either alone.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Lipedematous scalp is mainly caused by an increase in fat tissue under the skin and is different from lipedematous alopecia.

Anthralin is effective for psoriasis and alopecia with minimal systemic side effects but can irritate the skin.