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People with hidradenitis suppurativa often have lower vitamin D levels, weaker hip bones, and altered bone metabolism markers.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Estrogen deficiency, like after menopause or certain surgeries, leads to faster skin aging and health issues.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

The document concludes that freeze-dried platelet-rich plasma shows promise for medical use but requires standardization and further research.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Balding men had lower bone density, while balding women had higher hip bone density.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Bovine milk-derived exosomes may improve skin, hair, gut, brain, and bone health.

The consensus provided guidelines for treating the Female Athlete Triad and a system to decide when athletes can return to sports.

PRP treatments have shown mixed results for healing, and future research should focus on how PRP is used and which type is used.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

Testosterone therapy and surgeries like mastectomy improve transgender men's lives and mental health with low risks and high satisfaction.

Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.

The document concludes that individualized treatment and lifestyle changes are important for managing menopause symptoms and health risks.

miR-29 is a key factor that accelerates aging.

Innovative methods are reducing animal testing and improving biomedical research.

Eating disorders are serious, often undiagnosed conditions requiring early treatment, with anorexia being the most deadly and binge-eating the most treatable.

Higher early lead exposure is linked to delayed puberty in girls.

Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.