56 citations,
September 2013 in “Journal of Biochemistry and Molecular Biology” Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.
56 citations,
July 2005 in “Journal of The American Academy of Dermatology” Using both vertical and transverse sections gives a better diagnosis of alopecia than using one method alone.
55 citations,
August 2013 in “PloS one” Genetic differences between young and old Tan sheep explain why their fleece changes from curly to straight as they age.
53 citations,
March 2003 in “Journal of Investigative Dermatology” Human skin cells have a high-affinity system for biotin transport, crucial for skin health.
52 citations,
April 2016 in “Journal of the American Academy of Dermatology” Certain black hairstyling practices increase the risk of traction alopecia, requiring better management and education.
52 citations,
May 2015 in “PLOS Genetics” miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.
51 citations,
November 2010 in “Dermatologic Surgery” The research provides specific measurements for hair follicles that can improve hair transplant and regeneration techniques.
51 citations,
May 2010 in “Journal of Drug Targeting” Transcutol-containing vesicles improve minoxidil's skin penetration and hair growth promotion.
49 citations,
August 2004 in “The FASEB Journal” Mice with human skin protein K8 had more skin problems and cancer.
48 citations,
April 2019 in “ACS Applied Materials & Interfaces” A new method for delivering drugs through the skin using biodegradable particles was found to be effective.
48 citations,
June 2000 in “Japanese Journal of Cancer Research” Dimethylarsinic acid speeds up skin tumor growth in certain mice.
45 citations,
October 2015 in “BMC Genomics” Chicken feather growth involves specific genes and shares similarities with hair development.
44 citations,
August 2008 in “Plant journal” D'orenone stops root hair growth by disrupting auxin transport, but adding auxin can reverse this.
44 citations,
July 2005 in “Aesthetic Plastic Surgery” Hair transplantation successfully treated a woman's hair loss caused by a tight ponytail.
43 citations,
February 1999 in “Biochemical Journal” Overexpression of SSAT in mice causes hair loss, liver damage, and sensitivity to polyamine analogues.
42 citations,
January 2021 in “Journal of Clinical Medicine” Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.
42 citations,
December 2016 in “Cell Death & Differentiation” Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.
42 citations,
December 1990 in “The Journal of Dermatologic Surgery and Oncology” The study found that horizontal sections of scalp biopsies are better for analyzing hair loss, showing fewer hairs and more fine hairs in balding areas.
40 citations,
September 2014 in “Journal of cosmetic and laser therapy” Transepidermal drug delivery effectively treated areata alopecia with minimal side effects.
40 citations,
December 2006 in “Journal of The European Academy of Dermatology and Venereology” Minoxidil helps hair regrowth in traction alopecia.
40 citations,
May 1999 in “International Journal of Dermatology” Early diagnosis and treatment are crucial to prevent permanent hair loss from scalp trauma.
39 citations,
August 2017 in “Colloids and Surfaces B: Biointerfaces” 50-nm nanoparticles are better at penetrating skin and targeting hair follicles for drug delivery than 100-nm ones.
39 citations,
April 2016 in “Case Reports in Dermatology” Tofacitinib temporarily regrew hair in a man with alopecia, but its effects didn't last.
39 citations,
July 2015 in “British Journal of Dermatology” The pseudo 'fringe sign' can also appear in frontal fibrosing alopecia, not just in traction alopecia, showing that this condition may be more common than thought.
38 citations,
May 2015 in “Journal of controlled release” IMSG nanoparticles improve vaccine delivery and immune response through hair follicles.
37 citations,
May 2018 in “Frontiers in physiology” Certain RNA molecules are important for the development of wool follicles in sheep.
37 citations,
May 2018 in “Transgender health” Oral estradiol works for many transgender women but needs personalized dosing and monitoring.
37 citations,
June 2004 in “Human molecular genetics online/Human molecular genetics” The HCR gene contributes to psoriasis risk.
36 citations,
September 2018 in “Dermatologic Therapy” Oral minoxidil helps hair growth, is cost-effective, and mostly well-tolerated.
36 citations,
July 2017 in “Journal of controlled release” A new method allows for controlled, long-lasting delivery of retinoic acid through the skin with fewer side effects.