research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-Driven Melanoma Progression
Tadalafil and Finasteride may help treat aggressive melanoma.
Search
for
Sort by
Research
360-390 / 1000+ results research The Transcriptional Regulator Prdm1 Is Essential for the Early Development of the Sensory Whisker Follicle and Is Linked to the Beta-Catenin First Dermal Signal
Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.
research YKL-40: A Sensitive Biomarker for Early Androgenetic Alopecia and Early Hidden Metabolic Syndrome
High YKL-40 levels predict early hair loss and hidden metabolic issues.
research Hair and Nail Manifestations of Systemic Disease
Early baldness in men may indicate risks for obesity, metabolic syndrome, insulin resistance, and heart disease, similar to women with PCOS. Alopecia areata is often linked with autoimmune diseases and mental health issues. Certain hair disorders are due to genetic issues, and chemotherapy can cause hair loss through specific biological pathways. Iron deficiency's link to hair loss is still disputed.
research Liquid Chromatography-Mass Spectrometry for Simultaneous Determination of Spironolactone and Canrenone in Plasma Samples
A method was found to accurately measure spironolactone and canrenone in blood samples using liquid chromatography-mass spectrometry.
research Relationship of a Novel c.429delC Deletion in Hairless Gene HR with Alopecia in Two Families from Southern Punjab, Pakistan
A new mutation in the Hairless gene causes hair loss in two Pakistani families.
research Positioning of Low Alcohol or Alcohol-Free Minoxidil Formulation for the Management of Androgenetic Alopecia: Indian Perspective
Alcohol-free minoxidil is better for treating hair loss in Indian men.
research FLCN, A Novel Autophagy Component, Interacts With GABARAP And Is Regulated By ULK1 Phosphorylation
The protein FLCN is involved in cellular cleanup and is regulated by ULK1.
research Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model
Loss of OGG1 increases skin inflammation and auto-antibodies in lupus.
research A Novel Missense Mutation Affecting the Human Hairless Thyroid Receptor Interacting Domain 2 Causes Congenital Atrichia
A specific gene mutation causes congenital hair loss.
research Ovarian Leydig Cell Tumor in a Post-Menopausal Patient with Severe Hyperandrogenism
An 81-year-old woman's severe male hormone symptoms were caused by an ovarian tumor, which was treated with surgery.
research Plasma-Polymerized Antibacterial Coating of Ovine Tendon Collagen Type I Crosslinked with Genipin and Dehydrothermal-Crosslinked as a Cutaneous Substitute for Wound Healing
The GNP crosslinked scaffold with antibacterial coating is effective for rapid wound healing and infection prevention.
research Challenges in Treatment of Patients With Non-Classic Congenital Adrenal Hyperplasia
Treating non-classic congenital adrenal hyperplasia is complex because the benefits of hormone treatment must be weighed against potential health risks.
research Ovarian Intratumoral 21-Hydroxylase Deficiency in a Postmenopausal Hirsute Woman
A postmenopausal woman's masculine symptoms improved after surgery for a hormone-producing ovarian tumor.
research Beneficial Effects of Pumpkin Seed Oil as a Topical Hair Growth Promoting Agent in a Mice Model
Pumpkin seed oil may help hair grow and could be an alternative treatment for male hair loss.
research A Study of the Histopathological Features of Alopecias on Transverse Sections of Scalp Biopsies
Transverse scalp biopsy sections help diagnose different alopecias by showing hair follicle details and inflammation patterns.
research Bioactives in Nutricosmetics: A Focus on Caffeine from Tea to Coffee
Caffeine is beneficial for skin and hair treatments but needs better delivery methods to penetrate deeper skin layers.
research Red LED Light Therapy for Telogen Effluvium in Long COVID Patients With and Without Androgenetic Alopecia
Red LED light therapy helps reduce hair loss and improves hair regrowth in long COVID patients.
research Formulation and Evaluation of Herbal Cream for the Management of Androgenetic Alopecia
The herbal hair cream could help treat male pattern baldness by blocking a baldness-related enzyme and might be worth further investigation.
research Myotonic Dystrophy Type 1: Enhancing Patient Management Through Genetic and Multisystem Studies
There is no cure for myotonic dystrophy type 1, so treatment focuses on managing symptoms and complications.
research Sex Differences in Arterial Hypertension
Women may need different blood pressure guidelines than men for heart disease prevention.
research Male Androgenetic Alopecia
Hair loss in men can be slowed or reversed with treatments like minoxidil and finasteride, but it resumes if treatment stops. It may also indicate early heart disease and obesity.
research Lichen Planopilaris: Demographic, Clinical and Histopathological Characteristics and Treatment Outcomes of 25 Cases
Lichen planopilaris can be accurately diagnosed and effectively treated.
research Use of Cosmeceuticals During Pregnancy and Lactation
Use of cosmeceuticals during pregnancy and breastfeeding is not recommended due to insufficient safety data.
research Trichofolliculoma on Gluteal Area: A Unique Case Report
A rare benign skin nodule was found on the buttock, a unique location for this condition.
research Demographic Findings of Patients Diagnosed with Pernio and Comparison of Their Vitamin B12, Folate, and Ferritin Levels with a Control Group
Patients with pernio have lower vitamin B12 and ferritin levels than healthy people.
research Alopecia and Drugs: Exploring the Link Between Medications and Hair Loss
Some medications can cause hair loss, and it's important to track when the hair loss starts after taking a new medication.
research Evaluation of the Effect of a Formulation Containing Millet Extract, Wheat Germ Oil, L-Cystine, and Calcium Pantothenate Using Digital Phototrichogram in Women with Diffuse Alopecia
Millet extract, wheat germ oil, L-cystine, and calcium pantothenate reduced hair loss and improved hair growth in women with diffuse alopecia.
research Insulin Resistance and Metabolic Syndrome in Female Androgenetic Alopecia
There's no clear link between female pattern hair loss, insulin resistance, and metabolic syndrome.
research Revising the Role of the Androgen Receptor in Breast Cancer
The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.