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The NUDT15 gene variant causes severe side effects from azathioprine in some Indian patients.

Genetic screening for NUDT15 polymorphisms is crucial for patients taking azathioprine, especially in Asians.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Personalized thiopurine dosing based on NUDT15 genotyping can improve long-term outcomes for ulcerative colitis and Crohn's disease patients.

Screening for the NUDT15 gene variant can prevent severe side effects from thiopurine drugs in East-Asian people.

Thiopurines help treat IBD but require genetic testing to avoid side effects.

Monitor for early signs of azathioprine toxicity and check blood counts regularly.

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

Food intake, not genetics, affects how the body processes tadalafil and finasteride.

Azathioprine may help treat severe alopecia areata, but more research is needed.

Genetic testing is crucial before giving azathioprine to avoid severe side effects.

Effective treatment for hidradenitis suppurativa varies, with antibiotics commonly used and surgery as an option, but no single method is universally successful.

Azathioprine can cause severe blood issues and hair loss, needing careful monitoring and possible discontinuation.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

Lupus can cause different skin problems, and treatments like quitting smoking and using certain creams or medicines can help.

Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.

The NUDT15 R139C variant causes thiopurine-induced leukocytopenia through a different mechanism than previously thought in Japanese patients with inflammatory bowel disease.

The pseudo 'fringe sign' can also appear in frontal fibrosing alopecia, not just in traction alopecia, showing that this condition may be more common than thought.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.

The document gives treatment advice for various skin conditions, like using metronidazole for perioral dermatitis and minoxidil for hair loss.

UK medical students lack dermatology education, liver biopsy patients with risk factors show more fibrosis, and certain fungi resist drugs due to melanin; genetics may influence female hair loss.

Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.

A woman's sudden hair loss was linked to azathioprine use despite normal enzyme levels, and improved after stopping the drug and starting treatment.

Azathioprine can cause unusual hair loss, which may reverse after stopping the drug.

Mycophenolate mofetil can effectively treat autoimmune hepatitis when standard drugs fail.

Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.