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Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Women with PCOS are more likely to have fatty liver disease, especially if they have metabolic problems.

Lymphatic vessels are essential for hair follicle growth and skin regeneration.

Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.

Mutations in the PTPRQ gene cause significant balance issues in mice due to hair bundle defects in the inner ear.

Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.

Captopril reduces heart mass, while minoxidil has opposite effects and side effects.

New research on prostamide F2α has led to treatments for glaucoma and eyelash growth and may have more medical uses.

Foxi3 expression in developing teeth and hair is controlled by the ectodysplasin pathway.

TGF-β2 plays a key role in human hair growth and development.

A hair wrapped tightly around an infant's toe caused severe damage, requiring early removal and possibly surgery to prevent worse outcomes like amputation.

Fat cells are important for tissue repair and stem cell support in various body parts.

Hair loss in males involves inflammation, collagen buildup, and follicle damage, with severity increasing with age and baldness duration.

The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.

Hormone therapy and surgeries for transgender individuals affect their skin and hair, requiring specific dermatologic treatments and respectful care.

RACB in barley is crucial for cell polarity and nucleus positioning, aiding fungal infection.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Bee venom might be a good alternative treatment for various skin conditions because it has many healing properties.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.

New drug delivery methods can make natural compounds more effective and stable.

Behavioral dermatology treats skin problems by considering both emotional and physical factors.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.

The current system can't fully test all combination treatments, so alternative methods and regulatory flexibility are needed.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.