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Keratin from hair and wool is used in medical materials for healing and drug delivery.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Methotrexate is a promising and safe treatment for severe alopecia areata, with better results when combined with corticosteroids.

Akebia quinata and Akebia trifoliata have many health benefits and potential medical uses.

Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.

Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.

More high-quality research is needed to recommend flavonoids and saponins for clinical use.

Chitosan hydrogels are promising for repairing blood vessels but need improvements in strength and compatibility.

Acanthus ebracteatus Vahl. extract and verbascoside may help prevent hair loss and promote hair growth due to their anti-inflammatory properties and ability to protect against cell death.

Celery helps protect against developmental and brain issues in mice exposed to certain toxins.

Cepharanthine has many medicinal uses but needs improvement for better effectiveness.

Plumbagin may help protect cells, reduce inflammation, and has potential for treating various diseases, but more research is needed.

Hydroxychloroquine and chloroquine are not recommended for COVID-19 treatment due to insufficient evidence and safety concerns.

Tadalafil and Finasteride may help treat aggressive melanoma.

Nanoformulations improve luteolin's effectiveness as a cancer treatment.

N-acetylcysteine may prevent hair loss caused by chemotherapy.

Human dental pulp stem cell-conditioned medium, especially from hypoxic conditions, may help treat chemotherapy-induced hair loss and does not increase cancer risk.

Many pediatric epilepsy patients experience preventable severe adverse drug reactions, especially with certain medications and risk factors.

Thyroid disease can cause skin, hair, and nail problems, and treating the thyroid condition often improves these symptoms.

Many women who have used performance-enhancing drugs in Finland show high rates of mental health and substance use issues, and most have normal red blood cell counts.

Maxillariinae orchids contain 62 compounds with potential health benefits, including treating skin conditions and diseases like cancer and diabetes.

Adding 0.2% taurine to Angora rabbits' diet improves wool production and overall health.

Lotion with fucoidan from brown seaweed improved skin and reduced allergy symptoms in mice with dermatitis.

Eating plants from polluted areas can cause liver and kidney damage in rats due to toxic metals.

Using anabolic-androgenic steroids can cause skin problems like acne and hair loss in athletes.

Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.

Ziziphus spina-christi leaf extract lowered blood sugar and protected organs in diabetic rats.

The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.

The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.