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Long-term high-dose fluconazole can cause reversible hair loss.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Myrtle has various health benefits and potential for medicine development.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Stem cell niches support, regulate, and coordinate stem cell functions.

Latanoprost can make eyelashes longer, thicker, and darker.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.