24 citations
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March 2008 in “Neuroscience Research” This study revealed the complex three-dimensional innervation of touch domes in cat forepaw skin, highlighting the extensive branching and unmyelinated endings associated with Merkel cell–axon complexes.
19 citations
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February 2013 in “Journal of Investigative Dermatology” Touch domes in human skin are complex sensory structures not directly linked to hair.
October 2021 in “Journal of Investigative Dermatology” In this research, investigators used in vitro models to study the Merkel cell-neurite complex and reported that mechanical stimulation, similar to gentle touch, can induce molecular changes that are potentially relevant to hair growth, thus contributing to the understanding of its underlying mechanisms.
5 citations
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January 2024 in “Science Advances” In this study, researchers identified Tenascin-C as a marker for touch dome keratinocytes, which maintain themselves and can develop into Merkel cells following injury, showing they share molecular traits with various epidermal keratinocytes.
32 citations
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February 2019 in “eLife” This study identified key cells and pathways needed for the development of touch receptor patterns in mouse skin, notably that certain keratinocytes are crucial for innervation patterns, while Merkel cells and BMP signaling have distinct roles.
In this study, activation of Hedgehog signaling in both epithelial and stromal cells induced new hair follicles in adult mouse skin, but also resulted in the formation of tumors.
This study found that activating Hedgehog signaling in both epithelial and stromal cells can induce new hair follicles in adult mice, but this also leads to tumor formation.
85 citations
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July 2012 in “Cold Spring Harbor perspectives in biology” This article discusses the roles of epidermal stem cells in maintaining skin homeostasis and highlights how deregulation in signaling pathways may lead to cancer, but it reports no new experimental results.
1 citations
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January 2013 in “Journal of Investigative Dermatology” The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
31 citations
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November 2016 in “Cell Reports” This study reveals that somatosensory neurons in mouse skin exhibit structural plasticity during hair-follicle regeneration, which may temporarily impair the reliability of encoding gentle touch.
81 citations
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June 2014 in “Cold Spring Harbor perspectives in medicine” This article discusses recent advances in understanding the mechanisms of tactile end organs in the epidermis and hair follicles from studies of mouse hairy skin, but it reports no new clinical results.
January 2020 in “Durham e-Theses (Durham University)” This study concluded that UK law falls short in ensuring effective workplace equality for individuals with visible differences, suggesting amendments to the definition of disability and other legal reforms as potential solutions.
5 citations
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March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that Piezo2 channels are primarily located on sensory axon membranes in mechanosensory end organs, supporting a model where mechanical stimuli activate Aβ RA-LTMR neurons via axon protrusions.
50 citations
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September 2014 in “Stem cell reports” In this study, BLIMP1 was found to function in terminally differentiated epidermal cells to maintain homeostasis, rather than defining a sebocyte progenitor population.
January 2024 in “Wiadomości Lekarskie” This review discusses the advantages of robotic hair transplantation using the ARTAS iX robot compared to manual Follicular Unit Extraction, emphasizing enhanced precision, speed, and hair preservation capabilities, and reports no clinical results.
October 2025 in “HAL (Le Centre pour la Communication Scientifique Directe)” This research observed that, in domestic cats like Maine Coon and Rex breeds, a "piebald" coat color pattern is likely influenced by the Silver locus, although the specific mutations involved are yet to be published.
84 citations
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June 2013 in “Stem Cells Translational Medicine” This review discusses strategies for regenerating cutaneous nerve function in burn patients and highlights the potential role of autologous skin-derived adult stem cells in improving sensory recovery, but reports no new experimental findings.
1 citations
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June 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This symposium discussed recent advances in understanding skin as a sensory organ, emphasizing the interactions between itch, pain, and touch pathways and highlighting potential therapeutic targets.
June 2001 in “Annals of Internal Medicine” This letter highlights the challenge of implementing ethical principles in healthcare due to society's dependence on financial systems, suggesting this may hinder public health and environmental well-being.
This study identified the TALE homeodomain transcription factor Meis2 as a crucial regulator for the maturation and end-organ innervation of certain mechanoreceptors in mice, with its absence leading to altered sensory neuron structure and impaired touch sensitivity.
1 citations
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January 2002 in “ODU Digital Commons (Old Dominion University)” This review discusses the portrayal and enforcement of idealized masculinities in men's self-improvement advertising and reports no new empirical results.
July 2025 in “The Journal of Physiology” This study by Moore et al. (2025) provides the first evidence linking C-tactile afferents in humans to hair follicles, showing that these nerve fibers respond to hair movement rather than skin deformation, adding complexity to the understanding of their role in emotion and touch.
42 citations
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June 2021 in “Pharmaceutics” This review summarizes the use of 3D printing technologies for creating microneedles and evaluates their associated benefits, challenges, and regulatory considerations, but does not present new experimental results.
29 citations
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January 2021 in “G3 Genes Genomes Genetics” This study identified a 195 bp duplication in crested chickens that causes large crest feathers and can be associated with cerebral hernia in some breeds, but not all.
This study found that the transcription factor Meis2 is crucial for the maturation and innervation of sensory neurons responsible for light touch in mice, with its absence leading to reduced touch sensitivity.
This study found that the transcription factor Meis2 regulates the maturation and innervation of sensory neurons in mice, affecting their response to light touch.
Scalp micropigmentation usually needs two to three sessions, but factors like genetics, coverage area, and health conditions can require more.
45 citations
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April 2009 in “Journal of anatomy” This study examined the complex morphology of the cornified claw sheath in domesticated cats, uncovering structures and growth patterns that help maintain sharp claw tips essential for climbing and prey capture.
19 citations
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February 2023 in “Environmental and experimental botany” This review discusses the role of jasmonic acid and its conjugates in enhancing plant stress tolerance and balancing growth and defense mechanisms but provides no new experimental data.
February 2024 in “Infection and drug resistance” This study presented a case of tinea capitis in a 4-year-old without typical symptoms and traced the infection to Microsporum canis carried by domestic cats, highlighting the need for accurate diagnosis and appropriate treatment, especially in households with pets.