14 citations
,
July 2016 in “Fertility and Sterility” This study found that increasing the follicle number criteria for diagnosing PCOS to 25 per ovary excluded some women who continue to show evidence of metabolic risk.
13 citations
,
November 2017 in “Journal of Cellular and Molecular Medicine” This workshop reviewed various roles of endoplasmic reticulum chaperones, including calreticulin, in cellular signaling, disease states, and potential markers, but reports no new experimental findings.
13 citations
,
June 1989 in “Pediatric clinics of North America/The Pediatric clinics of North America” This article reviews assessment and management strategies for adolescent females with excessive hair growth and highlights the importance of evaluating potential androgen sources.
12 citations
,
March 2018 in “Medicine” This case report describes a 60-year-old woman with an ovarian Leydig cell tumor leading to elevated testosterone levels and hirsutism, highlighting the need to consider androgen-secreting tumors in similar postmenopausal cases.
11 citations
,
October 2011 in “Allergologia et immunopathologia” A girl with Netherton syndrome was able to eat wheat without allergies after a special treatment.
10 citations
,
February 2017 in “Hormone Molecular Biology and Clinical Investigation” This randomized clinical trial found that vitamin D supplementation did not significantly alter anthropometric or metabolic parameters in obese, insulin-resistant, and vitamin D-deficient women with polycystic ovary syndrome, whereas metformin effectively reduced body weight, BMI, waist circumference, total body fat, and serum glucose levels.
8 citations
,
September 2016 in “Asian journal of beauty & cosmetology” In this study, the methanol-ultrasound extract of Dendropanax morbifera leaf showed potential for use in functional cosmetics and hair growth products due to its high antioxidant capacity and effects on growth factor expression without cytotoxicity.
7 citations
,
December 2014 in “Gynecological Endocrinology” This study found that LC-MS/MS is a more reliable method than immunoassays for measuring serum 17OHP and androgen levels in women with hyperandrogenism.
6 citations
,
June 2017 in “Reproductive Biomedicine Online” This study found that women with polycystic ovary syndrome in China had elevated androgen levels compared to healthy controls, and suggests body weight management and SHBG and FAI testing are recommended for these women.
6 citations
,
April 2017 in “JAMA Dermatology” This study concluded that visits to emergency and urgent care centers for severe sunburn treatment are largely avoidable and contribute to significant healthcare costs.
6 citations
,
January 2017 in “Dermato-endocrinology” This study found that androsterone glucuronate (ADT-G) was the only androgenic metabolite sensitive to detecting differences between adult women with acne and controls, and its levels decreased with systemic treatment.
6 citations
,
May 2016 in “Urolithiasis” This study found that the risk of urinary stone disease increased significantly in patients with severe androgenetic alopecia, and that testosterone deficiency was more frequent among these patients.
6 citations
,
April 2019 in “Journal of Pediatric Endocrinology and Metabolism” In this study, metformin improved BMI, menstrual regularity, and symptoms of hyperandrogenism in adolescents with type 1 diabetes, but did not enhance glycemic control.
6 citations
,
July 2016 in “Gynecological Endocrinology” This study found that women with PCOS have higher total PSA levels than controls, and the total PSA level correlates positively with testosterone and free androgen index.
6 citations
,
May 2012 in “Archives of Dermatological Research” This study reports a novel missense mutation in the HR gene in a 68-year-old Hungarian woman with alopecia universalis and limb deformities, suggesting a need for further research on its role in these conditions.
5 citations
,
January 2014 in “Postepy Dermatologii I Alergologii” Among women with hirsutism studied, this research found a high prevalence of acne, particularly associated with polycystic ovarian syndrome and endocrine changes.
4 citations
,
January 2019 in “Obstetrics & gynecology science” This case study reported that a 51-year-old woman with hirsutism and voice thickening had a Leydig cell tumor detected by PET-CT, which normalized hormone levels and resolved symptoms after surgical removal.
3 citations
,
March 2018 in “Journal of Continuing Education in Nursing” This study found that a continuing education program significantly improved rural nurse practitioners' knowledge about assessing, diagnosing, and managing PCOS.
2 citations
,
June 2022 in “Scientific reports” This study found that women with PCOS had significantly higher hair cortisol concentrations, suggesting hyperactivation of the HPA axis may affect metabolic and inflammatory markers in those with elevated cortisol levels.
2 citations
,
January 2021 in “Our Dermatology Online” This study reported that alopecia areata mostly affects young Black African males, with very few associated pathologies observed in this population.
1 citations
,
October 2024 in “Cureus” This study reported that women with polycystic ovarian syndrome have higher serum irisin levels, which are associated with metabolic and hormonal imbalances, including hyperandrogenism, total cholesterol, and visceral fat.
1 citations
,
June 2025 in “Frontiers in Immunology” This study found that total serum IgE levels were elevated in patients with alopecia areata compared to controls, suggesting a possible involvement of IgE and Th2 cytokines in its pathogenesis.
1 citations
,
April 2021 in “Deneysel ve klinik tıp dergisi/Journal of experimental and clinical medicine” This study found that women with polycystic ovary syndrome in the Black Sea Region had higher levels of androgens, obesity, and insulin resistance, increasing their risk of metabolic syndrome compared to healthy women.
1 citations
,
October 2015 in “Renal Failure” This study observed a significant correlation between vertex pattern and total alopecia and the presence of urinary stones in patients under 60 years old.
December 2025 in “Journal of Skin and Stem Cell” This study found a higher prevalence of lipid abnormalities in individuals with androgenetic alopecia, especially in severe cases, highlighting the need for early screening and treatment to prevent cardiovascular complications.
This study found that patients with lichen planopilaris exhibit a higher pro-atherogenic lipid profile and elevated atherogenic indexes, suggesting a need for increased cardiovascular and lipid monitoring in these individuals.
This study found a significant association between androgenetic alopecia and metabolic syndrome, with AGA patients showing higher BMI, waist circumference, blood glucose, and cholesterol levels compared to controls.
In this case report, a 54-year-old woman with hirsutism was found to have a benign ovarian cystadenofibroma, which resolved after surgery, highlighting the importance of evaluating postmenopausal women for ovarian causes of androgen excess.
May 2021 in “Boletín latinoamericano y del Caribe de plantas medicinales y aromáticas” This study found that ethanolic extracts of Microsechium helleri showed notable antioxidant, hypoglycemic, and cardioprotective activities, while chloroformic extracts exhibited significant anti-inflammatory effects in experimental models.
May 2021 in “Journal of the Endocrine Society” This case report describes a 47-year-old woman diagnosed with a rare Sertoliform endometrioid carcinoma of the ovary, emphasizing its early-stage presentation and generally favorable prognosis.