February 2010 in “Journal of The American Academy of Dermatology” Most patients with alopecia areata in China have patchy hair loss, with total hair loss being less common, and the condition often starts around age 35 and can negatively affect quality of life, especially in more severe cases.
1 citations,
October 2020 in “Journal of Investigative Dermatology Symposium Proceedings” Platelet-Rich Plasma treatment improved hair growth and reduced inflammation in patients with patchy hair loss, but not in total hair loss, and Optical Coherence Tomography was useful in tracking this progress.
January 2022 in “Clinical, Cosmetic and Investigational Dermatology” A mix of methotrexate, corticosteroids, and topical minoxidil effectively treated severe total body hair loss, but caused stretch marks and needs long-term monitoring.
1533 citations,
October 2008 in “Endocrine reviews” Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
306 citations,
August 2011 in “Journal of cachexia, sarcopenia and muscle” Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.
166 citations,
March 2007 in “Hypertension” High androgen levels in young women with PCOS are linked to higher blood pressure.
120 citations,
June 2008 in “American Journal of Epidemiology” A simple screening method found that 6.3% of women in a semiurban area in Sri Lanka have polycystic ovary syndrome, with most showing menstrual irregularities.
118 citations,
February 2009 in “Fertility and Sterility” Most women with PCOS have high levels of male hormones, and free testosterone is the best marker for this.
110 citations,
November 1984 in “The American Journal of Medicine” A genetic defect in vitamin D receptors causes severe rickets and hair loss in children, but some heal as they age.
82 citations,
May 2016 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.
77 citations,
June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.
68 citations,
February 2019 in “Urology” Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.
67 citations,
February 2010 in “Acta Obstetricia et Gynecologica Scandinavica” Hirsutism is a strong sign of high male hormones and metabolic problems in women with PCOS, but acne and hair loss are not.
66 citations,
November 2001 in “European journal of endocrinology” Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.
62 citations,
July 2013 in “American Journal of Clinical Dermatology” Alopecia areata patients have higher oxidative stress and lower antioxidant levels.
61 citations,
January 2015 in “Hormones” Liraglutide caused significant weight loss in some obese women with PCOS, especially those with severe obesity and insulin resistance.
61 citations,
March 1990 in “Clinical pharmacology and therapeutics/Clinical pharmacology & therapeutics” Albendazole treatment for echinococcosis can cause serious side effects and requires close monitoring.
56 citations,
October 2018 in “Journal of The American Academy of Dermatology” Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.
53 citations,
March 1987 in “Journal of The American Academy of Dermatology” Minoxidil effectively regrows hair in male pattern baldness.
52 citations,
May 1982 in “The American journal of the medical sciences” Vitamin A toxicity likely caused the patient's high calcium levels.
50 citations,
March 2011 in “European Journal of Endocrinology” Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.
49 citations,
October 2017 in “Nutrients” Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.
48 citations,
November 2017 in “Journal of the American Academy of Dermatology” Tofacitinib 2% ointment helped hair regrow in 3 out of 10 patients with alopecia areata, but caused side effects like scalp irritation and raised cholesterol in some.
47 citations,
February 1998 in “Journal of bone and mineral research” A specific gene mutation causes vitamin D-resistant rickets and hair loss.
45 citations,
February 2011 in “Journal of the European Academy of Dermatology and Venereology” People with lichen planus have higher bad cholesterol and lower good cholesterol, increasing their risk for heart disease.
39 citations,
May 2004 in “Clinics in Dermatology” The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.
38 citations,
February 2019 in “Clinical Interventions in Aging” Dutasteride more effectively treats hair loss than finasteride, but may increase risk of altered libido.
37 citations,
January 2013 in “Postepy Dermatologii I Alergologii” Isotretinoin effectively reduces acne but causes dry skin, higher skin pH, more redness, and hair loss.
37 citations,
January 2010 in “Acta dermato-venereologica” People with early onset baldness have higher bad cholesterol and lower good cholesterol, increasing their heart disease risk.
35 citations,
March 2012 in “Experimental and Clinical Endocrinology & Diabetes” The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.