88 citations,
February 2011 in “Journal of Dermatological Science” Minoxidil helps hair growth by activating the β-catenin pathway.
88 citations,
May 2005 in “Journal of Dermatological Science” Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.
87 citations,
April 2018 in “Biochemical and Biophysical Research Communications” Exosomes from dermal papilla cells can help grow hair and might treat hair loss.
87 citations,
May 2012 in “PLOS Genetics” Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.
87 citations,
March 2005 in “Journal of Dermatological Science” Asiasari radix extract promotes hair growth and increases protein synthesis and cell proliferation.
86 citations,
February 2003 in “Journal of The American Academy of Dermatology” New methods improve how we test hair growth treatments, but challenges like slow hair changes and high costs remain.
86 citations,
December 2001 in “Experimental dermatology” Mutant mice help researchers understand hair growth and related genetic factors.
85 citations,
June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.
83 citations,
January 2015 in “World Journal of Stem Cells” Hair follicle regeneration needs special conditions and young cells.
82 citations,
March 2016 in “Autoimmunity reviews” Animal models have helped understand hair loss from alopecia areata and find new treatments.
82 citations,
January 2000 in “Hormone Research in Paediatrics” DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.
81 citations,
June 2010 in “Journal of Dermatological Treatment” The document concludes that minoxidil and finasteride are proven for hair growth, herbal remedies show promise, but more research is needed to confirm their effectiveness.
81 citations,
March 2009 in “Seminars in Cutaneous Medicine and Surgery” Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.
81 citations,
May 2007 in “Fertility and Sterility” Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.
80 citations,
January 1995 in “The American Journal of Medicine” Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.
79 citations,
January 2017 in “Dermatology practical & conceptual” Correcting nutrient deficiencies may help with hair loss, but the benefits of supplements without a deficiency are uncertain and could be harmful.
79 citations,
March 1999 in “The journal of investigative dermatology/Journal of investigative dermatology” Procyanidin compounds from grape seeds were found to significantly increase mouse hair growth.
78 citations,
February 2004 in “British Journal of Dermatology” Melatonin helps hair growth in women with hair loss.
78 citations,
March 1987 in “Journal of The American Academy of Dermatology” Minoxidil promotes hair growth but stops working when discontinued.
76 citations,
August 2018 in “International Journal of Cosmetic Science” Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
76 citations,
November 2010 in “Journal of The American Academy of Dermatology” Some African American women's central scalp hair loss is linked to genetics and past fungal scalp infections, with more research needed on other causes.
76 citations,
January 2007 in “American Journal of Clinical Dermatology” Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.
75 citations,
March 2014 in “Journal of Investigative Dermatology” Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.
75 citations,
June 1999 in “Pediatric Clinics of North America” The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.
73 citations,
June 2008 in “The Journal of Clinical Endocrinology and Metabolism” Polycystic ovarian shape is a genetic sign of PCOS and its hormonal and metabolic features can be inherited.
72 citations,
January 2011 in “Current Pharmaceutical Design” S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
72 citations,
December 1996 in “Journal of Investigative Dermatology” Human hair follicles can regenerate after removal, but with low success rate.
71 citations,
October 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” HFMs can help study hair growth and test potential hair growth drugs.
70 citations,
February 2017 in “Dermatologic Surgery” Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.
70 citations,
March 2016 in “Urologic Clinics of North America” The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.