12 citations
,
January 1991 in “Archives of dermatological research” Male hormones control a specific gene in hamster skin, with different hormones having varying effects.
11 citations
,
July 2015 in “Gene” This study found that dihydrotestosterone (DHT) suppresses prostaglandin E2 and TGF-β induced IGF-I gene promoter activity in osteoblasts, suggesting complex interactions among bone growth regulators and potential complications from anabolic steroid use.
11 citations
,
March 2014 in “Journal of The European Academy of Dermatology and Venereology” In this study, researchers found that androgen receptor gene polymorphism is associated with higher androgenetic alopecia grades and PSA levels in men with benign prostatic hyperplasia, but not with prostate cancer.
11 citations
,
April 2013 in “Journal of Agricultural and Food Chemistry” This study found that Monascus cursory extraction reduced baldness, prostate hyperplasia, and tumor incidence in animal models of androgen-related diseases, suggesting it may be a promising new therapeutic candidate.
11 citations
,
May 2010 in “Journal of Medicinal Chemistry” This study introduced a novel nonsteroidal androgen receptor antagonist that effectively controls sebum production in the golden Syrian hamster ear model through targeted follicular delivery.
11 citations
,
January 2001 in “Cambridge University Press eBooks” This article discusses cultural significance and psychological effects of hair growth variations but provides no new clinical findings.
10 citations
,
January 2019 in “Journal of Chromatography B” This study used a newly validated method to find that one-year finasteride treatment resulted in no significant differences in urinary androgen and prostaglandin levels between male pattern baldness patients and normal controls.
10 citations
,
March 1999 in “Comparative Haematology International” This study found that chronic administration of testosterone in mice induced an elevated EPO secretion response, possibly mediated through DHT, without affecting baseline EPO levels.
6 citations
,
September 2005 in “Expert Opinion on Pharmacotherapy” This review discusses the role of androgens in women's sexual health and highlights the need for further research on androgen replacement therapy to optimize quality of life, but reports no new clinical results.
6 citations
,
November 2020 in “Molecular and Cellular Endocrinology” This study found that androgens downregulate BMP2 in dermal papilla cells, inhibiting hair follicle stem cell differentiation, while BMP2 addition may restore hair lineage differentiation through the Wnt/β-catenin pathway.
5 citations
,
July 2003 in “Drug Development Research” In this study, using a novel topical androgen receptor suppressor, fluridil, significantly increased the percentage of growing hairs in males with androgenetic alopecia without systemic absorption or adverse side effects.
4 citations
,
April 1999 in “Dermatologic Clinics” Androgens, like DHT, affect hair growth and treatments like finasteride may help.
4 citations
,
October 1988 in “Clinics in Dermatology” This paper reviews current knowledge about androgens' role in androgenic alopecia and female hirsutism but presents no new clinical findings.
3 citations
,
March 2016 in “Phytotherapy Research” In laboratory tests, this study found that a novel natural composition targeting 5-alpha reductase and inflammatory pathways reduced disease-related markers in androgenetic alopecia and benign prostatic hyperplasia more effectively than finasteride.
2 citations
,
November 2020 in “Fertility Research and Practice” This study presents a new survey instrument that was cognitively tested for understanding menstrual cycle characteristics and androgen excess, including hirsutism, alopecia, and acne.
1 citations
,
April 2006 in “Seminars in Reproductive Medicine” This review discusses the multifactorial causes of female sexual dysfunction and reports no clinical results; it emphasizes the need for thorough evaluation before considering androgen therapy.
February 2017 in “Cancer Causes & Control” In this study, Swedish men carrying the AR haplotype H2 were found to have a significantly lower risk of prostate cancer compared to those with the more common H1 variant.
July 2015 in “Cambridge University Press eBooks” Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.
March 1998 in “Journal of dermatological science” Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.
July 2025 in “JOURNAL OF CLINICAL AND BIOMEDICAL SCIENCES” This study describes a case in which a 24-year-old woman with PCOS symptoms, including irregular menstruation and excessive hair growth, showed significant improvement in androgen levels, menstrual regularity, and hair reduction after undergoing a nine-month Ayurvedic treatment plan with dietary and lifestyle modifications.
12 citations
,
December 2017 in “Scientific reports” This study reported that pulverizing hair samples significantly improves the precision of testosterone measurement, with higher testosterone concentrations observed in men than in women.
90 citations
,
October 1983 in “British Journal of Dermatology” This study found that individuals with androgenic alopecia have an increased number of thin hairs (less than 40 microns in diameter) per cm², which may affect their clinical appearance.
11 citations
,
September 2020 in “Steroids” This study developed a new method using liquid chromatography-tandem mass spectrometry to measure multiple steroid hormones in hair, requiring significantly fewer strands than previous methods, with high accuracy and precision.
45 citations
,
August 2019 in “Dermatologic Therapy” This review discusses the physiopathology of androgenetic alopecia and evaluates various traditional and emerging treatments, reporting no new clinical results but highlighting the need for enhanced treatment strategies.
1 citations
,
November 2014 This chapter reviews patchy hair loss due to skin disease, nail disorders related to chronic trauma, and treatments for small carcinomas, but it reports no new clinical findings.
16 citations
,
October 2009 in “Dermatology” This study found that a cream containing spironolactone did not affect hair growth in hirsute women.
9 citations
,
June 2014 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” Blood AMH levels are higher in women with PCOS than in those with other similar conditions.
3 citations
,
March 2019 in “Post Reproductive Health” Testosterone replacement can help menopausal women with various symptoms, but should be used carefully and is not yet officially licensed in the UK for women.
403 citations
,
November 2005 in “Journal of Endocrinology” This review discusses the role of DHEA in intracrinology, highlighting its impact on breast and prostate cancer treatment and potential as a menopause therapy, but reports no new research findings.
305 citations
,
February 2007 in “Hormone and metabolic research” This review discusses the roles of androgens and estrogens in skin functions and disorders, and highlights the use of estrogen-progestin treatments and anti-androgens in managing hirsutism and acne, without reporting new results.