Search

everythinglearnresearchcommunity

for

Search:↓

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.

Dutasteride and finasteride affect different cell types differently.

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

Excess androgens may cause PCOS, not just be a symptom.

Testosterone therapy can help postmenopausal women with low sexual desire but needs more safety research and should be used with estrogen therapy.

Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.

Testosterone therapy can help improve sexual function, mood, and bone density in women with low androgen levels, but more research is needed on long-term safety.

PCOS may be influenced by factors in the blood, not just the ovaries.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

Too much androgen can cause hair loss; finasteride may help.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Androgens slow hair growth by altering Wnt signaling in balding cells.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Finasteride may improve prostate cancer treatment outcomes.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.