10 citations
,
November 2016 in “International Journal of Cosmetic Science” This study proposed the existence of a membrane-like structure between the cuticle and cortex in human hair, which may provide strong protection against external stimuli.
10 citations
,
March 2016 in “Development Growth & Differentiation” This study developed a bioengineering method to reconstruct embryonic dorsal skin from dissociated chick skin cells, allowing feather buds to form and grow in vitro, influenced by epithelial-mesenchymal interactions.
10 citations
,
September 2013 in “Nutrition” In this animal study, the ketogenic diet was associated with more severe biotin deficiency in biotin-deficient mice, suggesting that biotin supplementation is important when following this diet.
10 citations
,
January 2012 in “Journal of Biological Macromolecules” This study found that keratin film from human hair samples responded to damage from UV, bleaching, perming, and thermal treatments, making it a useful model for evaluating hair damage in product development.
10 citations
,
March 1990 in “The Journal of Dermatology” In this study, a psoriatic patient developed retinoid-induced granulation tissue after long-term oral etretinate therapy, suggesting prolonged use may lead to delayed wound healing.
10 citations
,
May 1978 in “Acta Dermato Venereologica” In this study, seven patients with generalized toxic erythema developed sterile pustules localized to hair follicles or sweat ducts, with most having a history of medication, solvent exposure, or infection.
9 citations
,
March 2023 in “Biomimetics” This review discusses current strategies and materials in tissue engineering for skin regeneration, emphasizing design approaches and suggesting directions for future research; it reports no new clinical findings.
9 citations
,
July 2022 in “British Journal of Pharmacology” In this study, topical MR blockade improved delayed wound healing in glucocorticoid-pretreated mice by promoting anti-inflammatory macrophages and enhancing angiogenesis.
9 citations
,
April 2022 in “Cell Communication and Signaling” This study found that the S100A4/NMIIA axis contributes to glioblastoma progression by recruiting and promoting migration of GBM cells along blood vessels, correlating with worse patient outcomes.
9 citations
,
October 2008 in “British Journal of Dermatology” This case report describes a patient with primary cutaneous natural killer/T-cell lymphoma, nasal type, where monoclonal Epstein–Barr virus genome expansion was associated with terminal aggressive behavior after an indolent clinical course.
8 citations
,
January 2024 in “Microorganisms” This study found that administering dupilumab to patients with moderate-to-severe atopic dermatitis over 12 weeks altered both fungal and bacterial skin microbiomes, increasing microbial diversity and decreasing colonization by Malassezia and Staphylococcus aureus at lesion sites.
8 citations
,
September 2021 in “EMBO Molecular Medicine” This study found that a 5-mer peptide called P5 promotes hair growth by activating adiponectin receptor 1, suggesting its potential use as a topical treatment for alopecia.
8 citations
,
February 2020 in “Journal of Drug Delivery Science and Technology” This study demonstrated that using PLGA nanoparticles to deliver chlorogenic acid significantly increased type 17 collagen production in human epidermal cells, indicating potential for improved skincare formulations.
8 citations
,
March 2019 in “Drugs - Real World Outcomes” This study reported that while general patient characteristics and adverse event incidence for eribulin were comparable between a healthcare claims database and post-marketing surveillance, significant differences in some side effects such as neutropenia were observed.
8 citations
,
August 2016 in “Acta dermato-venereologica” Timolol eye-drops can cause hair loss.
8 citations
,
March 2015 in “International Journal of Oncology” This study successfully established Tsc2-deficient embryonic stem cells from Eker rats and found these cells have distinct gene expression compared to non-mutant cells, which could help identify new therapeutic targets for TSC-related pathogenesis.
8 citations
,
February 2005 in “International Journal of Cosmetic Science” The study found that applying Bifidobacterium-fermented soy milk extract to human skin significantly reduced the decline in skin elasticity, suggesting its potential as a cosmetic ingredient to prevent skin aging.
8 citations
,
September 2002 in “Genes to Cells” This study suggests that label-retaining cells in the hair follicle contribute to follicular renewal, indicating a specific role in the hair cycle by proliferating during the late telogen phase.
8 citations
,
August 1987 in “The Journal of Dermatology” This study reports that the monoclonal antibody BKN-1 specifically stained basal cell epithelioma cells and certain normal skin structures, indicating a similarity in keratin expression between the tumor and follicular epithelium below the isthmus portion.
7 citations
,
August 2020 in “Genes” This study mapped gene expression in different skin structures of dogs, finding similarities to humans that support using dogs as models for human skin diseases.
7 citations
,
January 2020 in “Journal of Dermatology” This study described specific skin and hair follicle abnormalities in three Japanese patients with Cantu syndrome, which may relate to the regulation role of SUR2 in hair follicle growth.
7 citations
,
April 2013 in “Journal of Cellular Biochemistry” This study found that mice lacking CD61 had significantly shorter lower incisors compared to wild-type mice, suggesting CD61 is crucial for proper tooth growth and pre-ameloblast proliferation.
7 citations
,
February 2010 in “British Journal of Dermatology” A woman with a rare autoimmune disorder had a blister on her eye and unique immune reaction, which was effectively treated with medication.
7 citations
,
September 2004 in “International Journal of Cosmetic Science” This study demonstrated that visible light lightens blond hair more effectively than ultraviolet light, attacking melanin granules directly, whereas ultraviolet light primarily damages other hair tissues following washing.
7 citations
,
January 1990 in “Eisei kagaku” This study suggests that analyzing hair care product components left on hair using GC and GC-MS may provide a more objective forensic comparison than morphological examination.
6 citations
,
August 2024 in “The Journal of Dermatology” In this study, ozenoxacin was found to inhibit sebum production in insulin- and 5α-DHT-differentiated hamster sebocytes in a dose-dependent manner, suggesting potential benefits in acne management by combining antimicrobial activity against C. acnes with reduced sebum production.
6 citations
,
November 2021 in “Frontiers in immunology” This study suggests that STAT3 signaling in keratinocytes is crucial for maintaining skin homeostasis by regulating hair follicle-specific keratin genes, potentially impacting dermatitis development through microbe-triggered inflammatory responses.
6 citations
,
June 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” This study observed that the SREBF1 mutation c.1669C>T (p.Arg557Cys) may act as a recurrent hotspot mutation associated with both hereditary mucoepithelial dysplasia and autosomal-dominant ichthyosis follicularis with atrichia and photophobia syndrome, suggesting they may be on the same clinical spectrum.
6 citations
,
December 2018 in “International Journal of Cosmetic Science” This study found that a highly resistant structure, located at the interface between the cuticle and cortex of human hair, acts as a penetration barrier, which the authors propose to name the "cuticle anchored resistant base" or CARB.
6 citations
,
March 2018 in “Journal of Medicinal Food” This study demonstrated that water-soluble peptides from egg yolk, termed "hair growth peptide," stimulated human hair follicle cell growth and improved hair growth in female pattern hair loss.