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Different types of alopecia in children require specific diagnoses and treatments.

Cyproterone acetate is a safe treatment that causes mild feminizing effects and is more effective with added estrogens.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Androgens, like testosterone, are crucial for early testicular descent in rats.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.

Coats' Plus is a genetic disorder with eye abnormalities, brain calcification, poor growth, bone and skin issues, and movement disorders.

The HR protein's role as a repressor is essential for controlling hair growth.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Skin fat plays a key role in immune defense and healing beyond just storing energy.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.

Fluconazole is an effective antifungal medication with potential side effects and lacks official analytical methods for its determination.

Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.

Some treatments for folliculitis decalvans work well, with tetracyclines and a mix of rifampicin and clindamycin being most effective.