research Effects of SM-215 on Hair Growth by Hair Follicle Stimulation
This study found that SM-215 applied to mice increased hair follicle activity and capillary presence, promoting hair growth compared to non-treatment.
Search
for
Sort by
Research
30-60 / 1000+ results research Pre‐clinical evidences for the efficacy of tryptanthrin as a potent suppressor of skin cancer
This study reported that tryptanthrin, a compound found in indigo naturalis, effectively suppresses non-melanoma skin cancer in mice by reducing inflammation, inhibiting cell proliferation, and blocking specific signaling pathways associated with tumor growth.
research Effective Penetration of the Oxidized Keratin‐Rebonding Materials Into Hair Shafts Based on Charge Conversion
This study found that incorporating CTA2-BADG, a modified hair-rebonding compound, into damaged hair significantly improved surface morphology and tensile strength by using charge-conversion chemistry to enhance penetration into the hair shaft.
research Promotion of Hair Growth byRosmarinus officinalisLeaf Extract
This study found that topical Rosmarinus officinalis leaf extract improved hair regrowth in mice and inhibited androgen-associated mechanisms involved in hair loss.
research Scabicidal Potential of Coconut Seed Extract in Rabbits via Downregulating Inflammatory/Immune Cross Talk: A Comprehensive Phytochemical/GC-MS and In Silico Proof
This study found that coconut seed extract may effectively treat scabies in rabbits by improving infection signs and causing high mite mortality, suggesting its potential as a cost-effective herbal alternative.
research Effect ofCitrullus colocynthisSchrad fruits on testosterone-induced alopecia
In this study, petroleum ether extract of Citrullus colocynthis fruit effectively promoted hair growth in a mouse model of androgen-induced alopecia, showing comparable results to the standard treatment, finasteride.
research Supplemental figure 2 from Effect of Combined Treatment with Ursolic Acid and Resveratrol on Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate
In this study, the combined treatment of ursolic acid and resveratrol was evaluated for its effects on skin tumor promotion in female FVB mice. The combination was applied topically before TPA treatment and was found to significantly inhibit TPA-induced epidermal hyperproliferation, signaling pathways, and skin inflammation more effectively than either compound alone. Key signaling pathways affected included EGFR, STAT3, and NF-κB, among others. The combination also increased tumor suppressor levels and reduced proinflammatory cytokine expression. Overall, the combined treatment resulted in a greater reduction in tumor multiplicity and size, highlighting its potential as a more effective strategy for inhibiting skin tumor promotion compared to individual treatments.
research Supplemental figure 2 from Effect of Combined Treatment with Ursolic Acid and Resveratrol on Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate
In this study, the combined treatment of ursolic acid and resveratrol was evaluated for its inhibitory effects on skin tumor promotion in female FVB mice. The combination was applied topically before TPA treatment and was found to significantly inhibit TPA-induced epidermal hyperproliferation, signaling pathways, and skin inflammation more effectively than either compound alone. Key signaling pathways affected included EGFR, STAT3, and NF-κB, among others. The combination also increased tumor suppressor levels and reduced proinflammatory cytokine expression. Overall, the combined treatment resulted in a greater reduction in tumor multiplicity and size, highlighting its potential as a more effective strategy for preventing skin tumor promotion compared to individual treatments.
research The hair growth promoting effect of 4-O-methylhonokiol
This article discusses alopecia and the impact of hair loss on mental health, but it presents no new research findings and highlights the need for further studies.
research Anti-Alopecia Activity of Alkaloids Group from Noni Fruit against Dihydrotestosterone-Induced Male Rabbits and Its Molecular Mechanism: In Vivo and In Silico Studies
This study found that a sub-fraction of Noni fruit, FEA-3, showed hair growth-promoting effects in a rabbit model of androgenic alopecia, similar to Minoxidil.
research Tanshinone, a Natural NADPH Oxidase Inhibitor, Mitigates Testosterone-Induced Hair Loss
This study found that Tanshinone I and Tanshinone IIA from Salviae Miltiorrhizae Radix inhibited Nox activity heightened by testosterone in a mouse model, reducing H₂O₂ production and cell apoptosis, and reversing testosterone-induced hair growth suppression, suggesting their potential as treatments for androgenetic alopecia.
research 보문 : 마우스에서 하수오 열수추출물이 발모관련 효소활성과 유전자 발현에 미치는 영향
This study observed that Polygoni mulitiflori Radix water extracts accelerated hair regrowth in mice by enhancing enzyme activities and increasing IGF-1 gene expression related to hair growth.
research Procyanidin Oligomers Selectively and Intensively Promote Proliferation of Mouse Hair Epithelial Cells In Vitro and Activate Hair Follicle Growth In Vivo11The authors disclosed conflict of interest.
This study found that procyanidin oligomers, particularly dimers and trimers, significantly promoted hair growth in mice and hair epithelial cell cultures, suggesting potential use as hair growth agents.
research Cosmeceuticals in Dermatology
Cosmeceuticals may benefit skin health but need more research for efficacy and safety confirmation.
research 益氣補血湯이 C57BL/6 마우스의 育毛촉진 및 Cytokine 변화에 미치는 영향
In this study, Yikgeebohyul-tang promoted faster hair regrowth in C57BL6 mice, potentially linked to changes in cytokine levels and epidermal growth factor expression.
research Welche Pflanze für welche Hauterkrankung? Teil 2: Dermatophyten, chronisch‐venöse Insuffizienz, Photoprotektion, aktinische Keratosen, Vitiligo, Haarausfall, kosmetische Indikationen
This review discusses the effectiveness of various plant extracts, including Vitis vinifera and Aesculus hippocastanum, in treating dermatological conditions like venous insufficiency and actinic keratoses but reports no new clinical results.
research A review on skin aging: mechanisms and therapeutic strategies
This literature review indicates that skin aging involves complex interactions of both internal and external factors, leading to oxidative stress and cellular damage. The authors report promising results from novel anti-aging interventions, including antioxidants, senolytics, and herbal preparations, for slowing skin aging progression.
research Follicular and percutaneous penetration pathways of topically applied minoxidil foam
This study found that hair follicles are a significant and efficient pathway for the absorption of topical minoxidil foam in humans, with faster blood detection when follicles are open.
research Topically applied minoxidil may cause fetal malformation: A case report
This case report describes fetal malformations and placental abnormalities in a pregnant woman who applied minoxidil topically, suggesting potential risks of its use during pregnancy.
research Topically Applied Minoxidil in Baldness
Minoxidil helps hair growth, but results vary.
research Topically Applied Minoxidil in Baldness
Minoxidil, when applied to the scalp, can stimulate hair growth but effects vary, stop if treatment ends, and it may cause side effects like fluid retention.
research Relationship Between Contact Time of Applied Dose and Percutaneous Absorption of Minoxidil From a Topical Solution
This study found that minoxidil absorption through the skin increased with longer contact times, reaching over 75% of the maximum absorption within four hours.
research Compounded topical preparations in plaque psoriasis: Still a place for it in 2018?
This report describes the use of compounded topical preparations to treat two severe psoriasis patients and calls for further studies on their regulation, protocol, and stability evaluation.
research Effect of Rubbing on the Distribution of Topically Applied Drugs into the Hair Follicles
This study found that rubbing increased caffeine permeation into skin primarily via hair follicles, especially when applied against the natural hair direction.
research Fractional CO₂ laser combined with topical compound betamethasone for Vitiligo-Associated Leukotrichia: a retrospective study of 13 patients with limited effectiveness
In this study involving 13 patients with vitiligo-associated leukotrichia, minimal hair repigmentation was observed following treatment with fractional CO₂ laser and topical betamethasone, though the method was well tolerated, highlighting the need for further research to optimize treatment parameters.
research A pilot study evaluating the efficacy of topically applied niacin derivatives for treatment of female pattern alopecia
This study found that topical application of niacin derivatives significantly increased hair fullness in women with female pattern hair loss compared to a placebo after six months.
research Modern drug delivery strategies applied to natural active compounds
This review explores how colloidal drug delivery systems can enhance the stability, absorption, and bioavailability of phytochemicals, potentially rediscovering ancient compounds' therapeutic benefits and overcoming limitations like poor solubility and bioavailability.
research Oral Retinoids in Dermatology
Oral retinoids are effective for severe skin conditions but require careful use due to side effects.
research Topical use of systemic drugs in dermatology: A comprehensive review
This review discusses the topical use of systemic drugs for cutaneous disorders and reports a lack of strong evidence from randomized controlled trials, highlighting the need for larger comparative effectiveness studies.
research Topically applied N,N-Dimethylglycine Sodium Salt Enhances Human Skin Blood Flow by Inducing Endothelial Nitric Oxide Release
In this study, it was observed that topical application of N,N-Dimethylglycine Sodium Salt significantly increased skin microcirculation and blood flow in human subjects, suggesting potential benefits for skin health and conditions like dermatitis.