18 citations
,
November 2009 in “Archives of Dermatology” This study reported that topical calcipotriol did not reduce hypertrophic scar formation in women post reduction mammoplasty, but found a strong association between activated keratinocytes and scar formation.
18 citations
,
January 1997 in “British Journal of Dermatology” In this study, five women with androgenetic alopecia developed severe hypertrichosis on the face and limbs after using 5% topical minoxidil, which resolved after discontinuing the treatment.
18 citations
,
March 1984 in “BMJ” Minoxidil helps hair regrowth in alopecia, but more research needed.
17 citations
,
October 2021 in “Journal of Cosmetic Dermatology” This review found that topical immunotherapy and light/laser therapy may achieve over 50% hair regrowth efficacy in treating extensive alopecia areata in children, with no serious side effects observed.
17 citations
,
January 2016 in “Dermatology research and practice” In this study, topical Emu oil delayed burn wound healing but increased hair follicle activity and collagen synthesis in Balb/c mice.
17 citations
,
October 2009 in “Dermatology” This study reported that ultraviolet light treatment from a Kromayer lamp stimulated hair growth in four out of six patients with alopecia, whereas intralesional triamcinolone acetonide had a mixed effect.
17 citations
,
January 2006 in “Veterinary Dermatology” This study found that topical melatonin and vigorous brushing did not affect hair regrowth in clipped Siberian Huskies, although lumbosacral hairs grew significantly shorter than lateral thigh hairs.
17 citations
,
July 1988 in “International Journal of Dermatology” This study found psychological improvements related to hair problems, social discomfort, and self-esteem were greater in the group using minoxidil for early-stage androgenetic alopecia compared to the placebo group.
17 citations
,
March 1985 in “Journal of The American Academy of Dermatology” Minoxidil can lower blood pressure in some people.
17 citations
,
March 1985 in “Acta Dermato Venereologica” This study found that 1% topical minoxidil led to an increase in terminal hair growth in some individuals with alopecia areata, but only one case showed cosmetically satisfying results.
16 citations
,
December 2022 in “Expert Opinion on Drug Delivery” This study reviewed preclinical and clinical research and found that AFL-assisted topical drug delivery is considered safe and effective, enhancing drug efficacy, reducing treatment time and pain, and improving cosmetic and safety outcomes, but larger clinical trials are needed to confirm these benefits.
16 citations
,
October 2013 in “Anais Brasileiros de Dermatologia” In this case report, an elderly woman with erosive pustular dermatosis of the scalp showed complete closure of eroded areas after treatment with prednisone and topical tacrolimus, resulting in stable scarring alopecia.
16 citations
,
March 2009 in “Skin Pharmacology and Physiology” This study found that the penetration enhancer SEPA™ significantly increased both the speed and amount of hair growth from minoxidil in balding stumptail macaques compared to Rogaine®.
16 citations
,
December 2008 in “Journal of The American Academy of Dermatology” This study found that adherence to topical hydrocortisone in adults with atopic dermatitis was inconsistent and not significantly different across different medication vehicles, though disease severity improved markedly within 2 weeks.
16 citations
,
January 2007 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” A man had an allergic reaction to minoxidil, which stopped after he discontinued use and started corticosteroids.
16 citations
,
May 2006 in “The Journal of Dermatology” This study reported successful treatment of peeling skin syndrome using topical calcipotriol.
16 citations
,
August 2003 in “Journal of The American Academy of Dermatology” This preliminary study observed that topical nitrogen mustard was beneficial for only 1 out of 6 patients with extensive alopecia areata, with 4 patients not completing the trial.
16 citations
,
July 1989 in “British journal of dermatology/British journal of dermatology, Supplement” Topical cyclosporin A doesn't work for alopecia totalis because it doesn't penetrate the skin well.
16 citations
,
July 1988 in “International Journal of Dermatology” This study found that 2% minoxidil solution significantly increased nonvellus hair count in men with male pattern baldness compared to placebo during a 48-week trial.
16 citations
,
January 1986 in “Dermatology” In this study, 1% minoxidil lotion led to good results in 18% of male patients with androgenetic alopecia, but only 6% maintained regrowth one year after stopping treatment.
16 citations
,
April 1984 in “Archives of Dermatology” This study found that 1% minoxidil topical solution led to terminal hair regrowth in 25 out of 48 patients with alopecia areata, but only 11 patients achieved cosmetically acceptable results.
16 citations
,
October 1987 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that a topical vitamin D3 analogue had an anti-proliferative effect on guinea pig skin epidermis.
15 citations
,
April 2021 in “International Journal of Pharmaceutics” This study found that smaller mesoporous silica particles (400-600 nm) accumulated in skin furrows, suggesting their potential as carriers for enhancing the delivery of topical medications like metronidazole.
15 citations
,
November 2019 in “Cutaneous and Ocular Toxicology” This study investigated a liposomal hydrogel system for delivering minoxidil and tretinoin to treat androgenic alopecia, finding that the system enhanced skin permeation of minoxidil while retaining tretinoin on the skin and was non-irritating in animal tests, suggesting its potential effectiveness.
15 citations
,
May 2017 in “Journal of Dermatological Treatment” In this study, patients with alopecia areata experienced significant hair regrowth using topical latanoprost, minoxidil, or betamethasone valerate, with the addition of latanoprost enhancing the effectiveness of betamethasone valerate, showcasing these treatments as safe and effective options.
15 citations
,
December 2016 in “Advanced Pharmaceutical Bulletin” This study found that N-acetyl-glucosamine-loaded nanostructured lipid carriers showed promise for skin lightening in healthy volunteers by reducing melanin distribution.
15 citations
,
January 2015 in “Dermatitis” This review discusses the efficacy and safety of topical sensitizers for treating alopecia areata and reports no new clinical results; it emphasizes advancements in pediatric use, molecular mechanisms, and targeted delivery methods.
15 citations
,
July 2010 in “Journal of Allergy and Clinical Immunology” This study found that in mouse models, the novel NF-κB inhibitor DHMEQ improved symptoms of atopic dermatitis as effectively as tacrolimus or betamethasone.
15 citations
,
September 2008 in “Archives of Dermatological Research” In this study, topical 5% roxithromycin was effective in restoring hair growth in about half of individuals with androgenetic alopecia without causing adverse effects.
15 citations
,
March 2008 in “The Journal of Dermatology” In this case report, a patient with a history of discoid lupus erythematosus experienced an exacerbation of the condition after topical immunotherapy for alopecia areata, suggesting contact dermatitis as a potential trigger.